Cervicofacial necrotizing fasciitis caused by Haemophilus influenzae serotype e in a patient with Sjogren's syndrome, systemic lupus erythematosus and hypocomplementaemia
Azar M, Folk D, Henderson T, Mehra S, Vining E, Banach D. Cervicofacial necrotizing fasciitis caused by Haemophilus influenzae serotype e in a patient with Sjogren's syndrome, systemic lupus erythematosus and hypocomplementaemia. JMM Case Reports 2015, 2 DOI: 10.1099/jmmcr.0.000040.Peer-Reviewed Case Reports and Technical NotesSystemic lupus erythematosusNecrotizing fasciitisH. influenzaeSjogren's syndromeLupus erythematosusInvasive diseaseHaemophilus influenzae serotype eInvasive H. influenzae infectionsSerotype E.Cervicofacial necrotizing fasciitisMonomicrobial necrotizing fasciitisCervical necrotizing fasciitisH. influenzae infectionsBroad-spectrum antibioticsAdditional debridementB vaccinationEmergent debridementNeck painInfluenzae infectionIntraoperative culturesBlood culturesClinical dataImmunocompromised individualsFasciitisClinical importancePostmarket Modifications of High‐Risk Therapeutic Devices in Otolaryngology Cleared by the US Food and Drug Administration
Rathi VK, Ross JS, Samuel AM, Mehra S. Postmarket Modifications of High‐Risk Therapeutic Devices in Otolaryngology Cleared by the US Food and Drug Administration. Otolaryngology 2015, 153: 400-408. PMID: 26044785, DOI: 10.1177/0194599815587508.Peer-Reviewed Original ResearchConceptsClinical dataUS FoodDrug AdministrationPMA pathwayRetrospective cohort studyAdditional clinical dataPremarket approval pathwaySignificant clinical implicationsCohort studyHigh-risk medical devicesMedian numberClinical implicationsMarketing clearanceLife spanAdministrationSubstantial numberPMA applicationApproval pathwaySupplementsFDATherapeutic devicesPathway