Prenatal Cocaine Exposure and Adolescent Neural Responses to Appetitive and Stressful Stimuli
Yip SW, Potenza EB, Balodis IM, Lacadie CM, Sinha R, Mayes LC, Potenza MN. Prenatal Cocaine Exposure and Adolescent Neural Responses to Appetitive and Stressful Stimuli. Neuropsychopharmacology 2014, 39: 2824-2834. PMID: 24903650, PMCID: PMC4200493, DOI: 10.1038/npp.2014.133.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureFavorite-food cuesFunctional magnetic resonance imagingPCE adolescentsPrefrontal cortexVentral striatumNeural responsesBrain regionsAdolescents' neural responsesSubjective food cravingsDorsolateral PFC activationSubjective anxiety ratingsDorsolateral prefrontal cortexCocaine exposureSubcortical brain regionsDevelopment of addictionPFC activationEmotional regulationHuman adolescentsSubstance use disordersAppetitive processingMotivational controlAddiction vulnerabilityHippocampus activityFood cravings