Featured Publications
2023 American Heart Association Focused Update on Adult Advanced Cardiovascular Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care
Perman S, Elmer J, Maciel C, Uzendu A, May T, Mumma B, Bartos J, Rodriguez A, Kurz M, Panchal A, Rittenberger J, Association O. 2023 American Heart Association Focused Update on Adult Advanced Cardiovascular Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 2023, 149: e254-e273. PMID: 38108133, DOI: 10.1161/cir.0000000000001194.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsTemperature Management for Comatose Adult Survivors of Cardiac Arrest: A Science Advisory From the American Heart Association
Perman S, Bartos J, Del Rios M, Donnino M, Hirsch K, Jentzer J, Kudenchuk P, Kurz M, Maciel C, Menon V, Panchal A, Rittenberger J, Berg K, Council on Cardiovascular Surgery and Anesthesia; Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Peripheral Vascular Disease; Council on Cardiopulmonary C. Temperature Management for Comatose Adult Survivors of Cardiac Arrest: A Science Advisory From the American Heart Association. Circulation 2023, 148: 982-988. PMID: 37584195, DOI: 10.1161/cir.0000000000001164.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsThe Experiences And Needs Of Families Of Comatose Patients After Cardiac Arrest And Severe Neurotrauma: The Perspectives Of A National Key Stakeholders During An NIH-Funded Workshop (S21.006)
Muehlschlegel S, Perman S, Elmer J, Haggins A, Teixeira N, Huang J, Jansky L, Kirchner J, Kasperek-Wynn R, Lipman P, Fetters M, Dickert N, Silbergleit R. The Experiences And Needs Of Families Of Comatose Patients After Cardiac Arrest And Severe Neurotrauma: The Perspectives Of A National Key Stakeholders During An NIH-Funded Workshop (S21.006). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.1672.Peer-Reviewed Original ResearchWomen receive less targeted temperature management than men following out-of-hospital cardiac arrest due to early care limitations – A study from the CARES Investigators
Morris N, Mazzeffi M, McArdle P, May T, Burke J, Bradley S, Agarwal S, Badjatia N, Perman S, Group T. Women receive less targeted temperature management than men following out-of-hospital cardiac arrest due to early care limitations – A study from the CARES Investigators. Resuscitation 2021, 169: 97-104. PMID: 34756958, DOI: 10.1016/j.resuscitation.2021.10.036.Peer-Reviewed Original ResearchOvercoming Fears to Save Lives: COVID-19 and the Threat to Bystander CPR in Out of Hospital Cardiac Arrest
Perman S. Overcoming Fears to Save Lives: COVID-19 and the Threat to Bystander CPR in Out of Hospital Cardiac Arrest. Circulation 2020, 142: 1233-1235. PMID: 32795100, PMCID: PMC7515476, DOI: 10.1161/circulationaha.120.048909.Commentaries, Editorials and LettersPublic Perceptions on Why Women Receive Less Bystander Cardiopulmonary Resuscitation Than Men in Out-of-Hospital Cardiac Arrest
Perman S, Shelton S, Knoepke C, Rappaport K, Matlock D, Adelgais K, Havranek E, Daugherty S. Public Perceptions on Why Women Receive Less Bystander Cardiopulmonary Resuscitation Than Men in Out-of-Hospital Cardiac Arrest. Circulation 2019, 139: 1060-1068. PMID: 30779655, PMCID: PMC6386169, DOI: 10.1161/circulationaha.118.037692.Peer-Reviewed Original Research
2024
Advances in Enrolling Pregnant Persons Into Acute Care Clinical Trials, A Discussion With the Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (ICECAP) Trial Principal Investigators
Perman S, Meurer W, Silbergleit R, Jarman A. Advances in Enrolling Pregnant Persons Into Acute Care Clinical Trials, A Discussion With the Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (ICECAP) Trial Principal Investigators. Clinical Therapeutics 2024 PMID: 39613696, DOI: 10.1016/j.clinthera.2024.11.006.Peer-Reviewed Original ResearchThe Evolving Roles of Sex and Gender in Acute Care Medicine
Jarman A, Perman S. The Evolving Roles of Sex and Gender in Acute Care Medicine. Clinical Therapeutics 2024 PMID: 39609141, DOI: 10.1016/j.clinthera.2024.11.001.Peer-Reviewed Original ResearchThematic analysis of cardiac arrest survivors' and their caregivers' psychosocial intervention needs
Presciutti A, Siry-Bove B, Parker R, Wu O, Elmer J, Donnino M, Perman S, Vranceanu A. Thematic analysis of cardiac arrest survivors' and their caregivers' psychosocial intervention needs. General Hospital Psychiatry 2024 PMID: 39462752, DOI: 10.1016/j.genhosppsych.2024.10.015.Peer-Reviewed Original ResearchImpact of Time to Initiation of Targeted Temperature Management Among Patients with Out-of-Hospital Cardiac Arrest Undergoing Percutaneous Coronary Intervention
Kovach C, Leonard J, Messenger J, Waldo S, Perman S. Impact of Time to Initiation of Targeted Temperature Management Among Patients with Out-of-Hospital Cardiac Arrest Undergoing Percutaneous Coronary Intervention. Therapeutic Hypothermia And Temperature Management 2024 PMID: 39311798, DOI: 10.1089/ther.2024.0030.Peer-Reviewed Original ResearchOdds of neurologically favorable survivalOut-of-hospital cardiac arrestST-elevation myocardial infarctionNeurologically favorable survivalPercutaneous coronary interventionInitiation of targeted temperature managementTemperature management initiationFavorable survivalOverall survivalHospital dischargeVentricular tachycardiaTemperature managementSurvivors of ventricular tachycardiaVentricular fibrillationCoronary interventionAssociated with adverse clinical outcomesDelayed coronary angiographyProportion of patientsAdverse clinical outcomesPropensity-weighted analysisAssociated with decreased oddsAssociated with delayWithdrawal of life-sustaining careLife-sustaining careCoronary angiographyPreventing chronic distress in cardiac arrest survivors and their caregivers: Perspectives of multidisciplinary healthcare professionals
Presciutti A, Elmer J, Donnino M, Wu O, Parker R, Perman S, Vranceanu A. Preventing chronic distress in cardiac arrest survivors and their caregivers: Perspectives of multidisciplinary healthcare professionals. General Hospital Psychiatry 2024 PMID: 39341731, DOI: 10.1016/j.genhosppsych.2024.09.011.Peer-Reviewed Original ResearchVariability in temperature control practices amongst the Influence of Cooling duration on Efficacy in Cardiac Arrest Patients (ICECAP) trial
Beekman R, Perman S, Nguyen C, Kline P, Clevenger R, Yeatts S, Ramakrishnan R, Geocadin R, Silbergleit R, Meurer W, Gilmore E. Variability in temperature control practices amongst the Influence of Cooling duration on Efficacy in Cardiac Arrest Patients (ICECAP) trial. Resuscitation 2024, 203: 110397. PMID: 39278393, PMCID: PMC11466710, DOI: 10.1016/j.resuscitation.2024.110397.Peer-Reviewed Original ResearchTemperature Control Parameters Are Important: Earlier Preinduction Is Associated With Improved Outcomes Following Out-of-Hospital Cardiac Arrest
Beekman R, Kim N, Nguyen C, McGinniss G, Deng Y, Kitlen E, Garcia G, Wira C, Khosla A, Johnson J, Miller P, Perman S, Sheth K, Greer D, Gilmore E. Temperature Control Parameters Are Important: Earlier Preinduction Is Associated With Improved Outcomes Following Out-of-Hospital Cardiac Arrest. Annals Of Emergency Medicine 2024, 84: 549-559. PMID: 39033449, DOI: 10.1016/j.annemergmed.2024.06.007.Peer-Reviewed Original ResearchOut-of-hospital cardiac arrestNeurological outcomeDevice cohortCardiac arrestOut-of-hospital cardiac arrest patientsConsecutive out-of-hospital cardiac arrestPreinduction timeInterquartile rangeAssociated with improved outcomesCardiac arrest patientsProportion of patientsMultivariate logistic regression modelInverse probability of treatmentDevice timeInverse probability treatment weightsProbability of treatmentProspective trialsOHCA patientsArrest patientsClinical outcomesLogistic regression modelsCenter studyEarly initiationSecondary outcomesTreatment weightingCorrelation between hospital rates of survival to discharge and long-term survival for in-hospital cardiac arrest: Insights from Get With The Guidelines®-Resuscitation registry
Khera R, Aminorroaya A, Kennedy K, Chan P, Investigators A, Grossestreuer A, Moskowitz A, Ornato J, Churpek M, Starks M, Girotra S, Perman S. Correlation between hospital rates of survival to discharge and long-term survival for in-hospital cardiac arrest: Insights from Get With The Guidelines®-Resuscitation registry. Resuscitation 2024, 202: 110322. PMID: 39029583, PMCID: PMC11390317, DOI: 10.1016/j.resuscitation.2024.110322.Peer-Reviewed Original ResearchRisk-standardized survival ratesIn-hospital cardiac arrestWeighted kappa coefficientResuscitation RegistryLong-term survivalSurvivors of in-hospital cardiac arrestHierarchical logistic regression modelsCardiac arrestIn-hospitalLogistic regression modelsLong-term outcomesSurvival dataKappa coefficientHospital performanceIn-hospital survivalMedicare filesMedicare beneficiariesYears of ageHospitalization ratesPost-discharge survivalHospital dischargeRate of survivalMedicareHospitalRegression modelsEvaluating the National Institutes of Health Pipeline for Resuscitation Science Investigators
Coute R, Huebinger R, Perman S, Del Rios M, Kurz M. Evaluating the National Institutes of Health Pipeline for Resuscitation Science Investigators. Journal Of The American Heart Association 2024, 13: e035854. PMID: 38879460, PMCID: PMC11255749, DOI: 10.1161/jaha.124.035854.Peer-Reviewed Original ResearchMental Health Services in Postcardiac Arrest Care
Presciutti A, Perman S, Vranceanu A. Mental Health Services in Postcardiac Arrest Care. Neurocritical Care 2024, 1-4. PMID: 38684601, PMCID: PMC11518872, DOI: 10.1007/s12028-024-01992-6.Peer-Reviewed Original ResearchCan Clinical Scores Predict the Presence of Hypoxic Ischemic Brain Injury on Early Head Computed Tomography After Cardiac Arrest? (P6-2.001)
Nguyen C, Molligoda B, Kim N, Kitlen E, Wira C, Perman S, Khosla A, Miller P, Greer D, Gilmore E, Beekman R. Can Clinical Scores Predict the Presence of Hypoxic Ischemic Brain Injury on Early Head Computed Tomography After Cardiac Arrest? (P6-2.001). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206255.Peer-Reviewed Original ResearchThe Impact of Socioeconomic Status on Risk for Brain Death Following Out-of-Hospital Cardiac Arrest (P1-4.014)
Fung C, Kitlen E, Nguyen C, Kim N, Wira C, Perman S, Khosla A, Miller P, Greer D, Gilmore E, Beekman R. The Impact of Socioeconomic Status on Risk for Brain Death Following Out-of-Hospital Cardiac Arrest (P1-4.014). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206574.Peer-Reviewed Original ResearchExamining the Impact of Layperson Rescuer Gender on the Receipt of Bystander CPR for Women in Cardiac Arrest
Shelton S, Rice J, Knoepke C, Matlock D, Havranek E, Daugherty S, Perman S. Examining the Impact of Layperson Rescuer Gender on the Receipt of Bystander CPR for Women in Cardiac Arrest. Circulation Cardiovascular Quality And Outcomes 2024, 17: e010249. PMID: 38533649, PMCID: PMC11245171, DOI: 10.1161/circoutcomes.123.010249.Peer-Reviewed Original ResearchConceptsSexual assaultBystander cardiopulmonary resuscitationFear of sexual assaultSexual harassmentCardiopulmonary resuscitationRescuer's genderCardiac arrestOut-of-hospital cardiac arrestReceipt of bystander cardiopulmonary resuscitationPublic perceptionAdult US residentsOut-of-hospitalGenderAssaultUS residentsHarassmentIdentified themesPhysical injurySurvey respondentsFearWomenSurvey participantsMenThemesSurveyEmotional distress, social support, and functional dependence predict readiness for hospital discharge in a prospective sample of cognitively intact cardiac arrest survivors
Presciutti A, Enkhtsetseg N, Flickinger K, Coppler P, Ratay C, Doshi A, Perman S, Vranceanu A, Elmer J. Emotional distress, social support, and functional dependence predict readiness for hospital discharge in a prospective sample of cognitively intact cardiac arrest survivors. Resuscitation 2024, 198: 110166. PMID: 38452994, PMCID: PMC11088514, DOI: 10.1016/j.resuscitation.2024.110166.Peer-Reviewed Original ResearchSocial supportEmotional distressReadiness for Hospital Discharge ScaleTelephone Interview for Cognitive StatusENRICHD Social Support InventoryPost-discharge referralsHospital dischargeHospital Discharge ScaleSocial Support InventoryIn-hospital screeningAssociated with readinessPerceived social supportCognitive impairmentPosttraumatic Stress Disorder Checklist-5Cardiac arrestCA survivorsMultivariate linear regressionCardiac arrest survivorsDischarge ScaleHospital systemCognitive statusDistressing anxietySecondary analysisChecklist-5Hospital treatment