2020
Implantable Cardioverter Defibrillator Utilization and Mortality Among Patients ≥65 Years of Age With a Low Ejection Fraction After Coronary Revascularization
Goldstein S, Li S, Lu D, Matsouaka R, Rymer J, Fonarow G, de Lemos J, Peterson E, Pokorney S, Wang T, Al-Khatib S. Implantable Cardioverter Defibrillator Utilization and Mortality Among Patients ≥65 Years of Age With a Low Ejection Fraction After Coronary Revascularization. The American Journal Of Cardiology 2020, 138: 26-32. PMID: 33068540, DOI: 10.1016/j.amjcard.2020.09.056.Peer-Reviewed Original ResearchMeSH KeywordsAftercareAge FactorsAgedAged, 80 and overCardiologyCoronary Artery BypassDeath, Sudden, CardiacDefibrillators, ImplantableFemaleHeart FailureHumansMaleMedicareMortalityMyocardial InfarctionMyocardial RevascularizationPatient ReadmissionPercutaneous Coronary InterventionProportional Hazards ModelsSex FactorsStroke VolumeTachycardia, VentricularUnited StatesVentricular FibrillationConceptsImplantable cardioverter-defibrillator implantationImplantable cardioverter-defibrillatorIn-hospital ventricular arrhythmiasLow ejection fractionAssociated with ICD implantationEjection fractionVentricular arrhythmiasICD implantationCoronary revascularizationCABG-treated patientsPCI-treated patientsAssociated with lower mortalityCardiology follow-upIn-hospital revascularizationAll-cause mortalityAssociated with higher likelihoodICD utilizationHeart failure readmissionHeart failureYear of revascularizationCardioverter-defibrillatorRevascularization strategyMedicare claimsRevascularizationPatients
2016
Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non–ST-Segment–Elevation Acute Coronary Syndromes Clinical Trials
Kragholm K, Goldstein S, Yang Q, Lopes R, Schulte P, Bernacki G, White H, Mahaffey K, Giugliano R, Armstrong P, Harrington R, Tricoci P, Van de Werf F, Alexander J, Alexander K, Newby L. Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non–ST-Segment–Elevation Acute Coronary Syndromes Clinical Trials. Circulation 2016, 133: 1560-1573. PMID: 26957532, PMCID: PMC4856566, DOI: 10.1161/circulationaha.115.017299.Peer-Reviewed Original ResearchConceptsIncrease evidence-based careEvidence-based careClinical characteristicsClinical trialsAcute coronary syndrome trialsTranslation of clinical trialNon-ST segment elevation acute coronary syndromeNon-ST segment elevationPhase III clinical trialsPost-myocardial infarction mortalityIII clinical trialsClinical trial enrollmentInfarction mortalityAcute coronary syndromeClinical trial populationsAge strataGeneral populationTrial enrollmentIn-hospitalCoronary syndromeOlder patientsIncreased comorbiditiesTrial backgroundTrial populationEnrollment