2013
Anatomic Considerations in the Surgical Resection of Hepatocellular Carcinoma
Yoo PS, Enestvedt CK, Kulkarni S. Anatomic Considerations in the Surgical Resection of Hepatocellular Carcinoma. Journal Of Clinical Gastroenterology 2013, 47: s11-s15. PMID: 23632343, DOI: 10.1097/mcg.0b013e318280ce5f.Peer-Reviewed Original ResearchConceptsOrthotopic liver transplantationSurgical resectionHepatocellular carcinomaNonanatomic resectionLiver transplantationTreatment of HCCFormal anatomic resectionInferior oncologic outcomesResidual liver massExtent of resectionCommon primary malignancyFunctional hepatic parenchymaRelevant surgical anatomyLocoregional therapySystemic chemotherapyAnatomic resectionHepatic resectionOncologic outcomesPrimary malignancyCancer deathHepatic parenchymaSurgical techniqueCommon causeAdvanced casesResection
2012
Intermedin is overexpressed in hepatocellular carcinoma and regulates cell proliferation and survival
Guo X, Schmitz JC, Kenney BC, Uchio EM, Kulkarni S, H. CH. Intermedin is overexpressed in hepatocellular carcinoma and regulates cell proliferation and survival. Cancer Science 2012, 103: 1474-1480. PMID: 22625651, PMCID: PMC7659195, DOI: 10.1111/j.1349-7006.2012.02341.x.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaCell proliferationHepatocellular carcinoma (HCC) clinical samplesRat ischemic modelEarly-stage diseaseHuman hepatocellular carcinoma tumorsSNU-398 cellsHuman umbilical vascular endothelial cellsRole of intermedinDownregulation of Gli1Real-time RT-PCRDose-dependent mannerHepatocellular carcinoma tumorsVascular endothelial cellsMRNA expression levelsStage diseaseExtracellular signal-regulated kinaseSK-Hep-1Ischemic modelIMD expressionBenign liverCarcinoma tumorsImmunohistochemical analysisTherapeutic targetSignal-regulated kinase
2011
Laparoscopic repair of iatrogenic diaphragmatic hernia following radiofrequency ablation for hepatocellular carcinoma
Singh M, Singh G, Pandey A, H. CH, Kulkarni S. Laparoscopic repair of iatrogenic diaphragmatic hernia following radiofrequency ablation for hepatocellular carcinoma. Hepatology Research 2011, 41: 1132-1136. PMID: 22032681, DOI: 10.1111/j.1872-034x.2011.00865.x.Peer-Reviewed Original ResearchRadiofrequency ablationHepatic malignanciesDiaphragmatic herniaComplications of RFASymptomatic pleural effusionUnresectable hepatic malignanciesIatrogenic diaphragmatic herniaHepatic insufficiencyLaparoscopic repairPleural effusionHepatocellular carcinomaHerniaMalignancyAblationCirrhosisComplicationsPatientsCarcinomaEffusionFeverInsufficiency
2003
The sickest first? Disparities with model for end‐stage liver disease‐based organ allocation: One region's experience
Schaffer RL, Kulkarni S, Harper A, Millis JM, Cronin DC. The sickest first? Disparities with model for end‐stage liver disease‐based organ allocation: One region's experience. Liver Transplantation 2003, 9: 1211-1215. PMID: 14586883, DOI: 10.1053/jlts.2003.50192.Peer-Reviewed Original ResearchConceptsCadaver liversMELD scoreHepatocellular carcinomaOrgan allocationRegion patientsEnd-stage liver diseaseEquitable organ distributionMean MELD scoreMedian MELD scoreHigh MELD scoreLiver transplant programNumber of transplantationsOrgan Sharing regionsLiver recipientsPretransplantation mortalityMELD exceptionsLiver diseaseSingle centerUnited NetworkTransplant programsWaiting listTransplantationEvidence-based systemOrgan procurementTransplantation Network