Silibinin Inhibits Cell Growth and Induces Apoptosis through Cell-cycle Arrest in PC-3 Prostate Cancer Cells
Kim S, Kim K, Yu S, Jeon H, Jin Y, Lee C, Ahn S. Silibinin Inhibits Cell Growth and Induces Apoptosis through Cell-cycle Arrest in PC-3 Prostate Cancer Cells. Journal Of Life Science 2011, 21: 1573-1578. DOI: 10.5352/jls.2011.21.11.1573.Peer-Reviewed Original ResearchCell cycle check point proteinsCell cycle arrestDose-dependent mannerCheck point proteinsPC-3Cycle arrestProstate cancer cell line PC-3Cancer cell line PC-3Cyclin-dependent kinases 2/4/6PC-3 prostate cancer cellsCell line PC-3Milk thistleProstate cancer cells PC-3Prostate cancer cellsPC-3 cellsPI double stainingCancer cell linesCell growthInhibits cell growthChemopreventive effectsPoly (ADP-ribose) polymerase cleavageAnticancer effectsFlow cytometryRadical scavenger activityCaspase-3 activation