2023
Differences in Mortality Among Patients With Asthma and COPD Hospitalized With COVID-19
Liu Y, Rajeevan H, Simonov M, Lee S, Wilson F, Desir G, Vinetz J, Yan X, Wang Z, Clark B, Possick J, Price C, Lutchmansingh D, Ortega H, Zaeh S, Gomez J, Cohn L, Gautam S, Chupp G. Differences in Mortality Among Patients With Asthma and COPD Hospitalized With COVID-19. The Journal Of Allergy And Clinical Immunology In Practice 2023, 11: 3383-3390.e3. PMID: 37454926, PMCID: PMC10787810, DOI: 10.1016/j.jaip.2023.07.006.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseType 2 inflammationCOVID-19 severitySOFA scoreAirway diseaseNoneosinophilic asthmaSequential Organ Failure Assessment scoreOrgan Failure Assessment scoreSevere coronavirus disease 2019Higher SOFA scoreMedian SOFA scoreRetrospective cohort studyObstructive pulmonary diseaseOdds of mortalityLower SOFA scoresCells/μLCOVID-19 outcomesCoronavirus disease 2019Logistic regression analysisCOVID-19Clinical confoundersAsthma patientsCohort studyImmunological factorsClinical features
2021
Rationale and design of the prone position and respiratory outcomes in non-intubated COVID-19 patients: The “PRONE” study
Friedman E, Franzone J, Ko E, Corey K, Mock J, Alavian N, Schwartz A, Drummond M, Suber T, Linstrum K, Bain W, Castiblanco S, Zak M, Zaeh S, Gupta I, Damarla M, Punjabi N. Rationale and design of the prone position and respiratory outcomes in non-intubated COVID-19 patients: The “PRONE” study. Contemporary Clinical Trials 2021, 109: 106541. PMID: 34400361, PMCID: PMC8363159, DOI: 10.1016/j.cct.2021.106541.Peer-Reviewed Original ResearchConceptsNon-intubated COVID-19 patientsCOVID-19 patientsProne positioningProne positionRespiratory outcomesRespiratory rateCoronavirus disease 2019 (COVID-19) pneumoniaInvasive mechanical ventilationRandomized-controlled trialHigher acuity levelsDuration of effectLevel of careRespiratory supportHospitalized patientsMechanical ventilationSupplemental oxygenAcute pneumoniaOxyhemoglobin saturationRespiratory parametersAcuity levelsPatientsSecondary objectivePneumoniaOutcomesTrials