Rationale and design of the prone position and respiratory outcomes in non-intubated COVID-19 patients: The “PRONE” study
Friedman E, Franzone J, Ko E, Corey K, Mock J, Alavian N, Schwartz A, Drummond M, Suber T, Linstrum K, Bain W, Castiblanco S, Zak M, Zaeh S, Gupta I, Damarla M, Punjabi N. Rationale and design of the prone position and respiratory outcomes in non-intubated COVID-19 patients: The “PRONE” study. Contemporary Clinical Trials 2021, 109: 106541. PMID: 34400361, PMCID: PMC8363159, DOI: 10.1016/j.cct.2021.106541.Peer-Reviewed Original ResearchConceptsNon-intubated COVID-19 patientsCOVID-19 patientsProne positioningProne positionRespiratory outcomesRespiratory rateCoronavirus disease 2019 (COVID-19) pneumoniaInvasive mechanical ventilationRandomized-controlled trialHigher acuity levelsDuration of effectLevel of careRespiratory supportHospitalized patientsMechanical ventilationSupplemental oxygenAcute pneumoniaOxyhemoglobin saturationRespiratory parametersAcuity levelsPatientsSecondary objectivePneumoniaOutcomesTrials