2013
An RNA Degradation Machine Sculpted by Ro Autoantigen and Noncoding RNA
Chen X, Taylor DW, Fowler CC, Galan JE, Wang HW, Wolin SL. An RNA Degradation Machine Sculpted by Ro Autoantigen and Noncoding RNA. Cell 2013, 153: 166-177. PMID: 23540697, PMCID: PMC3646564, DOI: 10.1016/j.cell.2013.02.037.Peer-Reviewed Original ResearchConceptsRNA degradation machineDegradation machineY RNAsSingle-particle electron microscopyRing-shaped proteinRibosomal RNA maturationExoribonuclease polynucleotide phosphorylaseRo autoantigenNcRNAs actRRNA decayRNA maturationProtein cofactorsNoncoding RNAsSubstrate specificityDeinococcus radioduransStructured RNAsPolynucleotide phosphorylaseBiochemical assaysRNAOrthologsNcRNAPNPaseProteinSalmonella typhimuriumAtomic model
2008
Running Rings Around RNA: The role of Ro RNPs in RNA maturation and decay
Wolin S. Running Rings Around RNA: The role of Ro RNPs in RNA maturation and decay. The FASEB Journal 2008, 22: 527.3-527.3. DOI: 10.1096/fasebj.22.1_supplement.527.3.Peer-Reviewed Original ResearchY RNAsRNA bindsAnimal cellsRNA binding proteinRNA quality controlY-RNAsRo RNPsRNA maturationVertebrate cellsSmall RNAsCertain prokaryotesMammalian cellsD. radioduransLikely functionsStructured RNAsRunning ringsHelical portionBinding proteinRNABiochemical studiesEfficient maturationCentral cavityBacteriaProteinBinds