Platelet endothelial cell adhesion molecule‐1 modulates endothelial cell motility through the small G‐protein Rho
Gratzinger D, Canosa S, Engelhardt B, Maori J. Platelet endothelial cell adhesion molecule‐1 modulates endothelial cell motility through the small G‐protein Rho. The FASEB Journal 2003, 17: 1458-1469. PMID: 12890700, DOI: 10.1096/fj.02-1040com.Peer-Reviewed Original ResearchConceptsWound healing migrationSingle cell motilityCell motilityHealing migrationRho activityPECAM-1-positive endothelial cellsSmall G protein RhoGTPase-activating proteinsG-protein componentsImmunoreceptor tyrosine-based inhibitory motifG protein RhoEndothelial cell adhesion molecule-1Seven-transmembrane receptorsEndothelial cell motilityTyrosine-based inhibitory motifEndothelial cellsPECAM-1Endothelial cell migrationWound healing defectsExtracellular domainCell adhesion molecule-1Coordinated activationInhibitory motifCell migrationExtension formation