GATA4 mediates gene repression in the mature mouse small intestine through interactions with friend of GATA (FOG) cofactors
Beuling E, Bosse T, de Kerk D, Piaseckyj CM, Fujiwara Y, Katz SG, Orkin SH, Grand RJ, Krasinski SD. GATA4 mediates gene repression in the mature mouse small intestine through interactions with friend of GATA (FOG) cofactors. Developmental Biology 2008, 322: 179-189. PMID: 18692040, PMCID: PMC3031907, DOI: 10.1016/j.ydbio.2008.07.022.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiomarkersCell DifferentiationCell ProliferationEnterocytesGATA4 Transcription FactorGene Expression RegulationIntestinal AbsorptionIntestinal MucosaIntestine, SmallMiceMice, TransgenicNuclear ProteinsOrgan SpecificityOrganic Anion Transporters, Sodium-DependentRNA, MessengerSymportersTranscription FactorsTranscriptional ActivationConceptsFriend of GATAGene repressionCell fate determinationFamily of cofactorsMammalian small intestineProximal-distal patternRepression functionGata (FOG) cofactorsFate determinationCell lineage markersFOG cofactorsGATA factorsGATA4 mutantsGene activationTranscription factorsGATA4 functionIntestinal epithelial cellsGATA4Multiple tissuesRepressionLineage markersMouse small intestineCofactorEpithelial cellsGenes