Integrative analysis of gene and miRNA expression profiles with transcription factor–miRNA feed-forward loops identifies regulators in human cancers
Yan Z, Shah P, Amin S, Samur M, Huang N, Wang X, Misra V, Ji H, Gabuzda D, Li C. Integrative analysis of gene and miRNA expression profiles with transcription factor–miRNA feed-forward loops identifies regulators in human cancers. Nucleic Acids Research 2012, 40: e135-e135. PMID: 22645320, PMCID: PMC3458521, DOI: 10.1093/nar/gks395.Peer-Reviewed Original ResearchMeSH KeywordsFeedback, PhysiologicalGene Expression Regulation, NeoplasticGene Regulatory NetworksHumansMicroRNAsNeoplasmsTranscription FactorsTranscriptomeConceptsFeed-forward loopTranscription factorsMiRNA expression profilesExpression profilesNovel feed-forward loopCancer-related transcription factorsExpression dataTF target genesMiRNA-mRNA interactionsCommon target genesMiR-15/miRMiRNA expression dataMiRNA partnersTranscriptome changesTarget genesDifferential genesIntegrative analysisMultiple cancer typesGenesMiRNA expressionHuman cancersLiterature validationBiological conditionsMiRNAsRegulator