2019
The effects of MicroRNA deregulation on pre-RNA processing network in multiple myeloma
Adamia S, Abiatari I, Amin S, Fulciniti M, Minvielle S, Li C, Moreau P, Avet-Loiseau H, Munshi N, Anderson K. The effects of MicroRNA deregulation on pre-RNA processing network in multiple myeloma. Leukemia 2019, 34: 167-179. PMID: 31182781, PMCID: PMC6901818, DOI: 10.1038/s41375-019-0498-5.Peer-Reviewed Original ResearchConceptsMultiple myelomaPlasma cellsOvert multiple myelomaPatient outcomesMM cellsMM pathogenesisLet-7fMicroRNA deregulationRegulation of microRNAsCD138Certain miRsMyelomaMiRDependent gene expressionDeregulated expressionMiR-mediated regulationSignificant numberEpigenetic lesionsTarget genesMM genomesExpressionGene expressionEarly stagesCellsPatients
2010
Molecular Profiling of Extramedullary and Medullary Plasmacytomas Compared to Multiple Myeloma
Mahindra A, Amin S, Sohani A, Motyckova G, Patel K, Vallet S, Pozzi S, Santo L, Cirstea D, Toomey C, Michaelson J, Hochberg E, Dal Cin P, Rodig S, Hideshima T, Anderson K, Munshi N, Raje N. Molecular Profiling of Extramedullary and Medullary Plasmacytomas Compared to Multiple Myeloma. Blood 2010, 116: 4042. DOI: 10.1182/blood.v116.21.4042.4042.Peer-Reviewed Original ResearchMultiple myelomaMedullary plasmacytomaTissue microarrayMean overall survivalRisk of progressionPlasma cell disordersNew therapeutic approachesOverall survivalMale preponderanceMedian ageSolitary lesionMultiple lesionsPathological diagnosisPtch-1Plasma cellsTherapeutic approachesCell myelomaCell disordersPatientsSolid tumorsClonal proliferationMetastatic potentialPlasmacytomaMyelomaMolecular profiling