Bone Marrow Microenvironment Affects The Pathogenesis Of Multiple Myeloma Through Downregulation Of Alternative Splicing Factor Fox2 In Myeloma Cells
Song W, Zhang C, Hu Y, Gkotzamanidou M, Shah P, Shan W, Yang G, Amin S, Tai Y, Li Y, Sperling A, Rashid N, Magrangeas F, Minvielle S, Avet-Loiseau H, Anderson K, Li C, Munshi N. Bone Marrow Microenvironment Affects The Pathogenesis Of Multiple Myeloma Through Downregulation Of Alternative Splicing Factor Fox2 In Myeloma Cells. Blood 2013, 122: 3085. DOI: 10.1182/blood.v122.21.3085.3085.Peer-Reviewed Original ResearchAlternate splicingActin polymerizationCell linesRPMI8226 cell lineMM cell linesAlternative splicing regulatorsImportant splicing factorsAlternative splicing eventsGeneChip Human Exon 1.0 ST ArrayHuman Exon 1.0 ST ArrayPredominant nuclear localizationRNA-seq dataExpression levelsIGF-1 stimulationPost-translational changesGene expression levelsSplicing regulatorsGene functionStromal cell interactionsRNA splicingSplicing eventsSplicing factorsAlternative splicingRNA-seqMolecular role