Ethyl pyruvate reduces germ cell–specific apoptosis and oxidative stress in rat model of testicular torsion/detorsion
Payabvash S, Kiumehr S, Tavangar SM, Dehpour AR. Ethyl pyruvate reduces germ cell–specific apoptosis and oxidative stress in rat model of testicular torsion/detorsion. Journal Of Pediatric Surgery 2008, 43: 705-712. PMID: 18405719, DOI: 10.1016/j.jpedsurg.2007.12.063.Peer-Reviewed Original ResearchConceptsEthyl pyruvate solutionRinger's ethyl pyruvate solutionProtective effectRight testisTissue damageMPO activityTesticular torsionGroup 2Sperm countGerm cell apoptosis indicesLong-term testicular functionTesticular torsion/detorsionGerm cell-specific apoptosisLipid peroxidationApoptotic tissue damageTestis tissue damageTorsion/detorsionGroup 2 ratsAnti-inflammatory propertiesSprague-Dawley ratsGroup 24 hoursEpididymal sperm concentrationEthyl pyruvateCell apoptosis indexPyruvate solution