Poor Outcomes Related to Anterior Extension of Large Hemispheric Infarction: Topographic Analysis of GAMES-RP Trial MRI Scans
Payabvash S, Falcone GJ, Sze GK, Jain A, Beslow LA, Petersen NH, Sheth KN, Kimberly WT. Poor Outcomes Related to Anterior Extension of Large Hemispheric Infarction: Topographic Analysis of GAMES-RP Trial MRI Scans. Journal Of Stroke And Cerebrovascular Diseases 2019, 29: 104488. PMID: 31787498, PMCID: PMC8820410, DOI: 10.1016/j.jstrokecerebrovasdis.2019.104488.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAgedAnterior Cerebral ArteryCerebrovascular CirculationCerebrumClinical Trials as TopicClinical Trials, Phase II as TopicDiffusion Magnetic Resonance ImagingDisability EvaluationExtremitiesFemaleGlyburideHumansHypoglycemic AgentsInfarction, Anterior Cerebral ArteryInfarction, Middle Cerebral ArteryMaleMiddle AgedMiddle Cerebral ArteryPatient AdmissionPredictive Value of TestsRecovery of FunctionRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsLarge hemispheric infarctionInfarct volumeIndependent predictorsInfarct lesionsHemispheric infarctionHealth Stroke Scale total scorePost-stroke day 3Anterior cerebral artery territoryTotal scoreLeft MCA infarctLeg motor functionNIHSS total scoreHours of onsetOnly independent predictorPoor functional outcomeBorder zoneScale total scoreAnterior extensionMultivariate regression analysisVoxel-wise analysisLHI patientsAdmission NIHSSArtery territoryGlibenclamide treatmentMCA infarct