2024
Exploring the syndemic interaction between social, environmental and structural contexts of HIV infection in peri-mining areas in South Africa: a qualitative study
Chimoyi L, Ndini P, Oladimeji M, Seatlholo N, Mawokomatanda K, Charalambous S, Setswe G. Exploring the syndemic interaction between social, environmental and structural contexts of HIV infection in peri-mining areas in South Africa: a qualitative study. BMJ Open 2024, 14: e076198. PMID: 38521520, PMCID: PMC10961556, DOI: 10.1136/bmjopen-2023-076198.Peer-Reviewed Original ResearchConceptsFemale sex workersFocus group discussionsIn-depth interviewsInjection drug usersUptake of HIV prevention servicesHealthcare workersHIV prevention servicesHIV infectionHIV prevention programmesPre-exposure prophylaxisAssociated with HIV acquisitionAccessibility to alcoholSocio-behavioral factorsCommunity-based organisationsPreventive servicesHIV prevalencePrevention programmesAreas of South AfricaSyndemic factorsQualitative studyHIV transmissionHIV acquisitionInclusion criteriaFactors affecting peopleSex workers
2023
Transitional community adherence support for people leaving incarceration in South Africa: a pragmatic, open-label, randomised controlled trial
Mabuto T, Woznica D, Ndini P, Moyo D, Abraham M, Hanrahan C, Charalambous S, Zack B, Baral S, Owczarzak J, Hoffmann C. Transitional community adherence support for people leaving incarceration in South Africa: a pragmatic, open-label, randomised controlled trial. The Lancet HIV 2023, 11: e11-e19. PMID: 38071994, PMCID: PMC10894448, DOI: 10.1016/s2352-3018(23)00235-7.Peer-Reviewed Original ResearchConceptsHIV treatment servicesUsual care groupTreatment servicesAntiretroviral therapyPrimary outcomeCare groupSouth African National Clinical Trials RegisterDifferentiated service delivery modelsClinical Trials RegisterPeer-led interventionsPassive referralAdherence supportTrials RegisterUsual careAdherence clubsAdverse eventsTreat analysisHIV treatmentMultifactorial barriersCorrectional facilitiesService delivery modelsFinal analysisMental healthMonthsNational InstituteImpact of youth lay health workers on HIV service delivery in South Africa: A pragmatic cluster randomized trial of the Youth Health Africa program
Tollefson D, Dasgupta S, Setswe G, Reeves S, Charalambous S, Duerr A. Impact of youth lay health workers on HIV service delivery in South Africa: A pragmatic cluster randomized trial of the Youth Health Africa program. PLOS ONE 2023, 18: e0294719. PMID: 38033029, PMCID: PMC10688901, DOI: 10.1371/journal.pone.0294719.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnti-HIV AgentsFemaleHealth FacilitiesHIV InfectionsHumansMaleSouth AfricaTime FactorsYoung AdultConceptsHIV service deliveryHIV testingTreatment initiationIntervention facilitiesHealth workersYoung adultsAdolescents/young adultsProportion of patientsPragmatic clusterSecondary outcomesHIV positivityPrimary outcomeTreat analysisHIV servicesHIV programsHealth facilitiesHIVBaseline outcomesTrialsService deliveryNull trialsCareImmediate increaseOutcomesGreater improvement