2019
A novel combinatorial approach of quantitative microscopy and in silico modeling deciphers Arf1-dependent Golgi size regulation
Iyer P, Sutradhar S, Paul R, Bhattacharyya D. A novel combinatorial approach of quantitative microscopy and in silico modeling deciphers Arf1-dependent Golgi size regulation. The European Physical Journal E 2019, 42: 154. PMID: 31834534, DOI: 10.1140/epje/i2019-11920-x.Peer-Reviewed Original Research
2015
Intercentrosomal angular separation during mitosis plays a crucial role for maintaining spindle stability
Sutradhar S, Basu S, Paul R. Intercentrosomal angular separation during mitosis plays a crucial role for maintaining spindle stability. Physical Review E 2015, 92: 042714. PMID: 26565279, DOI: 10.1103/physreve.92.042714.Peer-Reviewed Original ResearchConceptsMammalian cellsProper spindle formationBipolar mitotic spindleDifferent motor proteinsMost mammalian cellsStable bipolar spindleProper segregationDaughter cellsSpindle stabilityCell divisionMitotic spindleSpindle formationSpindle instabilityBipolar spindleDifferent physiological constraintsCell biologyMotor proteinsChromosomal configurationsInterpolar microtubulesPhysiological constraintsSpindle lengthChromosomal patternCellsMechanistic modelCrucial roleA comprehensive model to predict mitotic division in budding yeasts
Sutradhar S, Yadav V, Sridhar S, Sreekumar L, Bhattacharyya D, Ghosh S, Paul R, Sanyal K. A comprehensive model to predict mitotic division in budding yeasts. Molecular Biology Of The Cell 2015, 26: 3954-3965. PMID: 26310442, PMCID: PMC4710229, DOI: 10.1091/mbc.e15-04-0236.Peer-Reviewed Original ResearchMeSH KeywordsChromosome SegregationCytoplasmCytoplasmic DyneinsDyneinsMicrotubulesMitosisModels, BiologicalSaccharomycetalesSpindle ApparatusConceptsCell divisionNuclear migrationChromosome segregationCytoplasmic microtubulesHigh-fidelity chromosome segregationMitotic cell divisionSystems biology approachSpindle orientationSpindle alignmentBiology approachMajor phylaMitotic eventsMitotic divisionMicrotubule dynamicsDistinct pathwaysYeastMinimal computational modelCortical dyneinPhylaDivisionEffects of perturbationsAscomycotaBasidiomycotaMigrationInterdependent interactions