2023
Dynamic microtubules slow down during their shrinkage phase
Luchniak A, Kuo Y, McGuinness C, Sutradhar S, Orbach R, Mahamdeh M, Howard J. Dynamic microtubules slow down during their shrinkage phase. Biophysical Journal 2023, 122: 616-623. PMID: 36659852, PMCID: PMC9989939, DOI: 10.1016/j.bpj.2023.01.020.Peer-Reviewed Original Research
2016
EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice
Thomas G, Bandopadhyay K, Sutradhar S, Renjith M, Singh P, Gireesh K, Simon S, Badarudeen B, Gupta H, Banerjee M, Paul R, Mitra J, Manna T. EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice. Nature Communications 2016, 7: 11665. PMID: 27225956, PMCID: PMC4894954, DOI: 10.1038/ncomms11665.Peer-Reviewed Original ResearchConceptsMicrotubule attachmentMicrotubule plus-end tracking protein EB1Plus-end tracking protein EB1Dynamic microtubulesMitotic chromosome alignmentMicrotubule latticeVertebrate cellsProtein complexesChromosome movementChromosome alignmentProtein EB1Biochemical experimentsEB1K-fibersDepletion resultsMicrotubulesVertebratesStructural studiesExtended structureSKA1EukaryotesKinetochoresImportant roleMitosisProtein
2015
A comprehensive model to predict mitotic division in budding yeasts
Sutradhar S, Yadav V, Sridhar S, Sreekumar L, Bhattacharyya D, Ghosh S, Paul R, Sanyal K. A comprehensive model to predict mitotic division in budding yeasts. Molecular Biology Of The Cell 2015, 26: 3954-3965. PMID: 26310442, PMCID: PMC4710229, DOI: 10.1091/mbc.e15-04-0236.Peer-Reviewed Original ResearchConceptsCell divisionNuclear migrationChromosome segregationCytoplasmic microtubulesHigh-fidelity chromosome segregationMitotic cell divisionSystems biology approachSpindle orientationSpindle alignmentBiology approachMajor phylaMitotic eventsMitotic divisionMicrotubule dynamicsDistinct pathwaysYeastMinimal computational modelCortical dyneinPhylaDivisionEffects of perturbationsAscomycotaBasidiomycotaMigrationInterdependent interactions
2013
Tug-of-war between opposing molecular motors explains chromosomal oscillation during mitosis
Sutradhar S, Paul R. Tug-of-war between opposing molecular motors explains chromosomal oscillation during mitosis. Journal Of Theoretical Biology 2013, 344: 56-69. PMID: 24333041, DOI: 10.1016/j.jtbi.2013.11.023.Peer-Reviewed Original Research