Intercentrosomal angular separation during mitosis plays a crucial role for maintaining spindle stability
Sutradhar S, Basu S, Paul R. Intercentrosomal angular separation during mitosis plays a crucial role for maintaining spindle stability. Physical Review E 2015, 92: 042714. PMID: 26565279, DOI: 10.1103/physreve.92.042714.Peer-Reviewed Original ResearchConceptsMammalian cellsProper spindle formationBipolar mitotic spindleDifferent motor proteinsMost mammalian cellsStable bipolar spindleProper segregationDaughter cellsSpindle stabilityCell divisionMitotic spindleSpindle formationSpindle instabilityBipolar spindleDifferent physiological constraintsCell biologyMotor proteinsChromosomal configurationsInterpolar microtubulesPhysiological constraintsSpindle lengthChromosomal patternCellsMechanistic modelCrucial role