EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice
Thomas G, Bandopadhyay K, Sutradhar S, Renjith M, Singh P, Gireesh K, Simon S, Badarudeen B, Gupta H, Banerjee M, Paul R, Mitra J, Manna T. EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice. Nature Communications 2016, 7: 11665. PMID: 27225956, PMCID: PMC4894954, DOI: 10.1038/ncomms11665.Peer-Reviewed Original ResearchConceptsMicrotubule attachmentMicrotubule plus-end tracking protein EB1Plus-end tracking protein EB1Dynamic microtubulesMitotic chromosome alignmentMicrotubule latticeVertebrate cellsProtein complexesChromosome movementChromosome alignmentProtein EB1Biochemical experimentsEB1K-fibersDepletion resultsMicrotubulesVertebratesStructural studiesExtended structureSKA1EukaryotesKinetochoresImportant roleMitosisProtein