Fasting-Induced Increase in Type II Iodothyronine Deiodinase Activity and Messenger Ribonucleic Acid Levels Is Not Reversed by Thyroxine in the Rat Hypothalamus*
Diano S, Naftolin F, Goglia F, Horvath T. Fasting-Induced Increase in Type II Iodothyronine Deiodinase Activity and Messenger Ribonucleic Acid Levels Is Not Reversed by Thyroxine in the Rat Hypothalamus*. Endocrinology 1998, 139: 2879-2884. DOI: 10.1210/en.139.6.2879.Peer-Reviewed Original ResearchPTU-treated ratsThyroid glandShort-term fastingPropylthiouracil treatmentEuthyroid controlsThyroid hormonesEuthyroid animalsDeiodinase activityMessenger RNAFasted ratsAdjacent periventricular regionsMessenger ribonucleic acid levelsQuantitative in situ hybridization analysisHypothalamic paraventricular nucleusRelease of TRHGroups of fasted ratsT4-treated ratsLevels of thyroid hormonesHypothalamus of ratsDeclining plasma levelsRibonucleic acid levelsThyroid hormone levelsSerum thyroid hormonesFasting-induced increaseWeeks of PTU administration