Die Expression der ζ-Kette des T-Zell-Rezeptors als Prognosemarker bei Kopf-Hals-Karzinomen
Müller D, Lang S, Roskrow M, Wollenberg B. Die Expression der ζ-Kette des T-Zell-Rezeptors als Prognosemarker bei Kopf-Hals-Karzinomen. Laryngo-Rhino-Otologie 2002, 81: 516-520. PMID: 12173063, DOI: 10.1055/s-2002-33289.Peer-Reviewed Original ResearchConceptsTumor-infiltrating lymphocytesZeta chain expressionPeripheral blood lymphocytesT cell receptorTumor stageZeta chainCorrelated to clinical dataMechanisms of immune suppressionT cell receptor zeta chainSystemic immune defectsAnti-tumor responsesEarly tumor stageHigher tumor stageSquamous cell carcinomaHead and neckT cell activationFlow cytometric analysisSystemic immunomodulationImmune defectsInfiltrating lymphocytesClinical aggressivenessCell carcinomaImmune suppressionBlood lymphocytesSCCHNKorrelation von FDG-PET und MRT/CT mit der Histopathologie in Primärdiagnostik, Lymphknotenstaging und Rezidivdiagnostik von Kopf-Hals-Tumoren
Pöpperl G, Lang S, Dagdelen O, Jäger L, Tiling R, Hahn K, Tatsch K. Korrelation von FDG-PET und MRT/CT mit der Histopathologie in Primärdiagnostik, Lymphknotenstaging und Rezidivdiagnostik von Kopf-Hals-Tumoren. RöFo 2002, 174: 714-720. PMID: 12063600, DOI: 10.1055/s-2002-32215.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedDiagnosis, DifferentialFemaleFluorodeoxyglucose F18HumansLymph NodesLymphatic MetastasisMagnetic Resonance ImagingMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingNeoplasms, Unknown PrimaryOtorhinolaryngologic NeoplasmsPrognosisRetrospective StudiesSensitivity and SpecificityTomography, Emission-ComputedTomography, X-Ray ComputedConceptsLymph node metastasisCervical lymph node metastasisDiagnosis of primary tumorLymph node involvementPrimary tumorPre-surgical diagnosisTumor recurrenceNode metastasisFDG-PETNode involvementPrimary lesionHistopathological findingsDiagnostic value of FDG-PETStaging of head and neck cancerPrimary lymph node involvementDiagnosis of tumor recurrenceHead and neck cancerTumor diameter <Occult primary tumorDetect tumor recurrenceMorphological imaging modalitiesRecurrent tumorsPT1 stageNeck cancerPatient prognosis