Featured Publications
Kaposi’s Sarcoma-Associated Herpesvirus K3 and K5 Proteins Down Regulate Both DC-SIGN and DC-SIGNR
Lang SM, Bynoe MO, Karki R, Tartell MA, Means RE. Kaposi’s Sarcoma-Associated Herpesvirus K3 and K5 Proteins Down Regulate Both DC-SIGN and DC-SIGNR. PLOS ONE 2013, 8: e58056. PMID: 23460925, PMCID: PMC3584050, DOI: 10.1371/journal.pone.0058056.Peer-Reviewed Original ResearchAmino Acid MotifsCell Adhesion MoleculesCell MembraneDown-RegulationEndocytosisHEK293 CellsHerpesvirus 8, HumanHumansImmunoprecipitationLectins, C-TypeLysosomesProteasome Endopeptidase ComplexProtein StabilityProtein Structure, TertiaryProteolysisReceptors, Cell SurfaceStructure-Activity RelationshipTyrosineUbiquitinationViral Proteins
2004
Vpx proteins of SIVmac239 and HIV-2ROD interact with the cytoskeletal protein α-actinin 1
Mueller S, Jung R, Weiler S, Lang S. Vpx proteins of SIVmac239 and HIV-2ROD interact with the cytoskeletal protein α-actinin 1. Journal Of General Virology 2004, 85: 3291-3303. PMID: 15483243, DOI: 10.1099/vir.0.80198-0.Peer-Reviewed Original ResearchMeSH KeywordsActininAmino Acid SequenceAnimalsBiological TransportChlorocebus aethiopsCOS CellsCytoplasmHIV-2Molecular Sequence DataProlineProtein Structure, TertiaryRetroviridae ProteinsSequence AlignmentSimian immunodeficiency virusTransfectionTwo-Hybrid System TechniquesViral Regulatory and Accessory ProteinsConceptsPre-integration complexNuclear localization signalNuclear importProline-rich C-terminal domainClassical import pathwayEfficient nuclear importTwo-hybrid screenAlpha-actinin 1Α-actinin 1C-terminal domainLoss of interactionImport pathwayLocalization signalCellular proteinsNuclear localizationSequence elementsCytoskeletal proteinsVpx geneVpx proteinsQuiescent cellsAA proteinViral proteinsProteinVirion particlesRed-capped mangabeys