2023
Sporadic pituitary adenoma with somatic double-hit loss of MEN1
Hong C, Alanya H, DiStasio M, Boulware S, Rimmer R, Omay S, Erson-Omay E. Sporadic pituitary adenoma with somatic double-hit loss of MEN1. Pituitary 2023, 26: 488-494. PMID: 37438451, DOI: 10.1007/s11102-023-01336-1.Peer-Reviewed Original ResearchPortable MRI to assess optic chiasm decompression after endoscopic endonasal resection of sellar and suprasellar lesions.
Hong C, Lamsam L, Yadlapalli V, Parasuram N, Mazurek M, Chavva I, Lalwani D, Zabinska J, Schiff S, Manes R, Vining E, Rimmer R, Kimberly W, Sheth K, Omay S. Portable MRI to assess optic chiasm decompression after endoscopic endonasal resection of sellar and suprasellar lesions. Journal Of Neurosurgery 2023, 139: 1664-1670. PMID: 37347618, DOI: 10.3171/2023.5.jns23174.Peer-Reviewed Original ResearchConceptsEndoscopic endonasal surgeryOptic nerve decompressionEndonasal surgerySuprasellar lesionsNerve decompressionOptic chiasmThird ventricleConventional MRIOptic chiasm compressionEndoscopic endonasal resectionChiasm compressionPreoperative imagingSingle institutionEndonasal resectionMRI availabilityRoutine MRISignificant interrater reliabilitySuprasellar pathologiesSurgeryNeurosurgical oncologyLinear mixed-effects modelsPortable MRIPatientsMRIMixed-effects modelsTrends in clinical trials for olfactory dysfunction in the COVID‐19 era
Wang V, Abdou H, Sheth A, Manes R, Rimmer R. Trends in clinical trials for olfactory dysfunction in the COVID‐19 era. International Forum Of Allergy & Rhinology 2023, 13: 1958-1961. PMID: 36851905, DOI: 10.1002/alr.23144.Peer-Reviewed Original ResearchDefining the Clival Recess Surgical Corridor and Clival Classification System for Approach to Sellar Pathology
Yaghi N, Mazur-Hart D, Larson E, Munger D, Nugent J, Richie E, Rimmer R, Fleseriu M, Dogan A, Geltzeiler M, Ciporen J. Defining the Clival Recess Surgical Corridor and Clival Classification System for Approach to Sellar Pathology. Operative Neurosurgery 2023, 24: e315-e321. PMID: 36716036, DOI: 10.1227/ons.0000000000000609.Peer-Reviewed Original Research
2022
Endoscopic Medial Orbitotomy for Lateral Access to Anterior Cranial Base Pathology
Rimmer R, Geltzeiler M. Endoscopic Medial Orbitotomy for Lateral Access to Anterior Cranial Base Pathology. The Laryngoscope 2022, 133: 1336-1338. PMID: 36259774, DOI: 10.1002/lary.30445.Peer-Reviewed Original ResearchProfiles of Odorant Specific Performance in Olfactory Testing
Schlosser RJ, Soler ZM, Mace J, Farrell N, Rimmer R, Alt JA, Ramakrishnan VR, Edwards TS, Smith TL. Profiles of Odorant Specific Performance in Olfactory Testing. American Journal Of Rhinology And Allergy 2022, 37: 26-34. PMID: 36069003, DOI: 10.1177/19458924221124692.Peer-Reviewed Original ResearchConceptsOlfactory dysfunctionPsychophysical testingNon-CRS subjectsVariety of etiologiesHealthy control adultsSinus complaintsTrigeminal functionChronic rhinosinusitisNasal polypsSniffin' SticksOlfactory testingDiagnostic groupsControl adultsOlfactory assessmentHyposmicSimilar findingsEtiologyAdultsUnique profileCRSRhinosinusitisSpecific odorantsPathophysiologyDysfunctionCohortEndoscopic Endonasal Eustachian Tube Obliteration as a Treatment for Tension Pneumocephalus After Translabyrinthine Resection of Vestibular Schwannoma
Ji KSY, Rimmer R, Dogan A, Cetas JS, Ciporen JN, Sanusi O, Gupta S, Geltzeiler M. Endoscopic Endonasal Eustachian Tube Obliteration as a Treatment for Tension Pneumocephalus After Translabyrinthine Resection of Vestibular Schwannoma. Otology & Neurotology 2022, 43: e856-e860. PMID: 35970161, DOI: 10.1097/mao.0000000000003606.Peer-Reviewed Original ResearchConceptsEustachian tube obliterationCerebrospinal fluid leakV-Loc sutureTranslabyrinthine resectionVestibular schwannomaMental statusThird ventricleComputed tomographyFluid leakTension pneumocephalusCerebellopontine angle massPatient's mental statusLateral skull base surgeryRight frontal lobeOriginal surgical siteSkull base surgeryTranslabyrinthine excisionDevastating complicationLateral ventricleResection cavityMAIN OUTCOMESurgical siteFrontal lobePneumocephalusSuture techniqueEvaluating Distance Bias in Chronic Rhinosinusitis Outcomes
Gill AS, Beswick DM, Mace JC, Menjivar D, Ashby S, Rimmer RA, Ramakrishnan VR, Soler ZM, Alt JA. Evaluating Distance Bias in Chronic Rhinosinusitis Outcomes. JAMA Otolaryngology - Head & Neck Surgery 2022, 148: 507-514. PMID: 35511170, PMCID: PMC9073660, DOI: 10.1001/jamaoto.2022.0268.Peer-Reviewed Original ResearchConceptsSF-6D scoresAcademic tertiary care centerTertiary care centerEndoscopic sinus surgeryCross-sectional studyComorbidity burdenChronic rhinosinusitisSinus surgeryCare centerMedical Outcomes Study Short FormDisease severitySNOT-22 total scoresChronic rhinosinusitis outcomesMedical comorbid conditionsAppropriate medical therapyBaseline disease severitySinonasal Outcome TestCohort of patientsSNOT-22 scoresOverall symptom severityResidence zip codeAssociation of distanceSNOT-22Median ageMedical therapyEndoscopic Endonasal Eustachian Tube Obliteration for Cerebrospinal Fluid Rhinorrhea: A Case Series and Scoping Review
Rimmer R, Lilly G, Gupta S, Ciporen J, Detwiller K, Cetas J, Dogan A, Geltzeiler M. Endoscopic Endonasal Eustachian Tube Obliteration for Cerebrospinal Fluid Rhinorrhea: A Case Series and Scoping Review. Operative Neurosurgery 2022, 22: 345-354. PMID: 35867077, DOI: 10.1227/ons.0000000000000158.Peer-Reviewed Original ResearchConceptsCerebrospinal fluid rhinorrheaEustachian tube obliterationLateral skull base surgeryCase seriesSkull base surgeryPrior surgical attemptsRetrospective chart reviewSmall case seriesInitial success rateBarbed suture techniqueNew case seriesTranslabyrinthine resectionChart reviewRetrospective seriesVestibular schwannomaRevision surgeryLumbar drainSurgical attemptsRevision casesPatientsBarbed sutureSuture techniqueSurgeryValuable option
2021
Determinants of survival in sinonasal and skull base chondrosarcoma: An analysis of the National Cancer Database
Rimmer RA, Mace JC, Andersen PE, Cetas JS, Ciporen JN, Dogan A, Smith TL, Geltzeiler M. Determinants of survival in sinonasal and skull base chondrosarcoma: An analysis of the National Cancer Database. International Forum Of Allergy & Rhinology 2021, 12: 699-713. PMID: 34704402, DOI: 10.1002/alr.22909.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseSkull base chondrosarcomaOverall survivalDeterminants of survivalAdjuvant treatmentCancer DatabaseMultivariate Cox regression modelingMalignant chondroid tumorsMainstay of treatmentCox regression modelingOptimal treatment regimensCases of sinonasalRegression modelingCritical neurovascular structuresConventional external beamAdjuvant radiationBetter OSFavorable OSComplete resectionTreatment regimensTumor gradeHigher OSInclusion criteriaSkull base regionMortality riskAssociation of statins with quality of life and olfaction in patients with chronic rhinosinusitis
Rimmer RA, Mace JC, Gill A, Alt J, Detwiller K, Geltzeiler M, Smith TL, Farrell NF. Association of statins with quality of life and olfaction in patients with chronic rhinosinusitis. International Forum Of Allergy & Rhinology 2021, 12: 237-239. PMID: 34510817, DOI: 10.1002/alr.22880.Peer-Reviewed Original ResearchOpioid use after endoscopic skull base surgery: A descriptive, prospective, longitudinal cohort study
Rimmer RA, Scott B, Pailet J, Farrell NF, Mace JC, Detwiller KY, Smith TL, Dogan A, Gupta S, Andersen P, Cetas J, Geltzeiler M. Opioid use after endoscopic skull base surgery: A descriptive, prospective, longitudinal cohort study. International Forum Of Allergy & Rhinology 2021, 12: 160-171. PMID: 34309220, DOI: 10.1002/alr.22871.Peer-Reviewed Original ResearchConceptsPrevious opioid useEndoscopic skull base surgeryOpioid useHeadache disordersSkull base surgeryCohort studyMean postoperative pain scoreNonsteroidal anti-inflammatory drugsGreater opioid useOutpatient opioid useTotal opioid usePostoperative pain managementPostoperative pain scoresProspective cohort studyPostoperative day 8Longitudinal cohort studyHistory of headacheAnti-inflammatory drugsExcess opioidsOpioid consumptionOpioid exposurePain scoresPreoperative questionnairePublic health crisisAdult patientsCumulative comorbidity burden does not worsen outcomes in management of chronic rhinosinusitis
Gill AS, Mace JC, Rimmer R, Ramakrishnan VR, Beswick DM, Soler ZM, Manor J, Orlandi RR, Smith TL, Alt JA. Cumulative comorbidity burden does not worsen outcomes in management of chronic rhinosinusitis. International Forum Of Allergy & Rhinology 2021, 12: 28-38. PMID: 34259379, PMCID: PMC8716416, DOI: 10.1002/alr.22866.Peer-Reviewed Original ResearchConceptsFunctional Comorbidity IndexSF-6D scoresBaseline SNOT-22Chronic rhinosinusitisComorbidity burdenSNOT-22CRS treatmentShort Form-6D scoresHigher comorbidity burdenNasal Outcome TestEffect of comorbidityHealth utility valuesCross-sectional studyElectronic medical recordsComorbidity indexLund-MackayMedical comorbiditiesTomography ScoreCRS patientsSinonasal qualitySurgical therapyMedical recordsTreatment outcomesOutcome measuresHealth utility
2020
Quantitative determination of the optimal temporoparietal fascia flap necessary to repair skull‐base defects
Siu A, Rangarajan SV, Rabinowitz MR, Luginbuhl A, Rimmer RA, Chitguppi C, Farrell C, Nyquist GG, Rosen MR, Evans JJ. Quantitative determination of the optimal temporoparietal fascia flap necessary to repair skull‐base defects. International Forum Of Allergy & Rhinology 2020, 10: 1249-1254. PMID: 32634294, DOI: 10.1002/alr.22609.Peer-Reviewed Original ResearchPostoperative Anatomic Position of Mandibular Free Flap Neocondyles Affects Patient Symptoms
Swendseid B, Philips R, Rimmer R, Goldman RA, Luginbuhl AJ, Curry J, Krein H, Heffelfinger R. Postoperative Anatomic Position of Mandibular Free Flap Neocondyles Affects Patient Symptoms. Facial Plastic Surgery & Aesthetic Medicine 2020, 23: 36-41. PMID: 32614617, DOI: 10.1089/fpsam.2020.0110.Peer-Reviewed Original ResearchConceptsTemporomandibular jointAnterior displacementPostoperative symptomsDentulous patientsNormal dietCondylar reconstructionInferior displacementReconstructed condyleAxial imagingPostoperative computed tomography scansMandibular condyleComputed tomography scanFree flap reconstructionFree flap casesJaw painPostoperative dietConsecutive patientsPatient's symptomsSingle institutionTomography scanFlap reconstructionAnteroposterior alignmentPosterior aspectMAIN OUTCOMEJaw function
2019
Endoscopic Nasopharyngectomy Combined with a Nerve‐sparing Transpterygoid Approach
Geltzeiler M, Turner M, Rimmer R, Zenonos G, Hebert A, Snyderman C, Gardner P, Fernandez‐Miranda J, Wang EW. Endoscopic Nasopharyngectomy Combined with a Nerve‐sparing Transpterygoid Approach. The Laryngoscope 2019, 130: 2343-2348. PMID: 31841236, DOI: 10.1002/lary.28479.Peer-Reviewed Original ResearchConceptsInternal carotid arteryCartilaginous Eustachian tubeBony eustachian tubeEustachian tubeEndoscopic endonasal approachCarotid arteryTranspterygoid approachEndoscopic nasopharyngectomyPalatine nervePetrous internal carotid arteryPetrous carotidBloc resectionSurgical managementNasopharyngeal tumorsSkull base exposureVidian nerveForamen lacerumMeckel's caveEndoscopic eraNasopharyngectomyInadvertent exposureEndonasal approachNerveArteryCadaveric specimensRate of rhinosinusitis and sinus surgery following a minimally destructive approach to endoscopic transsphenoidal hypophysectomy
Rimmer RA, Vimawala S, Chitguppi C, Reilly EK, Graf AE, Fastenberg JH, Evans JJ, Rosen MR, Rabinowitz MR, Nyquist GG. Rate of rhinosinusitis and sinus surgery following a minimally destructive approach to endoscopic transsphenoidal hypophysectomy. International Forum Of Allergy & Rhinology 2019, 10: 405-411. PMID: 31765522, DOI: 10.1002/alr.22482.Peer-Reviewed Original ResearchConceptsFunctional endoscopic sinus surgeryTranssphenoidal hypophysectomyEndoscopic transsphenoidal hypophysectomyChronic rhinosinusitisSinus surgeryNasoseptal flapExcellent long-term patientNasal Outcome Test (SNOT-22) scoresPrior chronic rhinosinusitisRetrospective chart reviewCourse of antibioticsEndoscopic sinus surgeryLong-term patientsOutcome Test scoresPreoperative levelsChart reviewTurbinate lateralizationRecurrent tumorsPrimary indicationSingle institutionPituitary surgeryRhinosinusitisPatientsSurgeryPosterior septectomyEvaluation of cranial base repair techniques utilizing a novel cadaveric CPAP model
Chitguppi C, Rimmer RA, Garcia HG, Koszewski IJ, Fastenberg JH, Nyquist GG, Rosen MR, Huntley C, Rabinowitz MR, Evans JJ. Evaluation of cranial base repair techniques utilizing a novel cadaveric CPAP model. International Forum Of Allergy & Rhinology 2019, 9: 795-803. PMID: 30748124, DOI: 10.1002/alr.22313.Peer-Reviewed Original ResearchConceptsContinuous positive airway pressureRepair techniquesSphenoid sinusEarly postoperative usePositive airway pressureObstructive sleep apneaPositive pressure ventilationEndonasal skull base surgeryFresh human cadaver headsSkull base surgerySkull base defectsPostoperative useAirway pressurePressure ventilationSleep apneaRecent guidelinesPositive pressureTime of initiationHuman cadaver headsDural sealantBase defectsCadaveric modelCadaver headsOnlayCranial base
2018
The Role of Free Tissue Transfer in the Management of Chronic Frontal Sinus Osteomyelitis
Rimmer RA, Duffy AN, Knops AM, Rabinowitz MR, Koszewski IJ, Rosen MR, Ortlip T, Heffelfinger RN, Garcia HG, Evans JJ, Nyquist GG, Curry JM. The Role of Free Tissue Transfer in the Management of Chronic Frontal Sinus Osteomyelitis. The Laryngoscope 2018, 129: 1497-1504. PMID: 30549281, DOI: 10.1002/lary.27669.Peer-Reviewed Original ResearchConceptsFree tissue transferFrontal sinus osteomyelitisFrontal bone osteomyelitisTissue transferExtensive debridementOverall complication rateRetrospective chart reviewFrontal sinus infectionChronic frontal sinusitisNumber of surgeriesPlanned courseSignificant debridementPostoperative antibioticsChart reviewComplication rateDefinitive treatmentPostoperative infectionSinus infectionOpen surgeryRecurrent infectionsSurgical interventionSingle institutionSurgical dataFrontal sinusitisSimultaneous cranioplastyA cadaveric model for measuring sinonasal continuous positive airway pressure—a proof‐of‐concept study
Rimmer RA, Chitguppi C, Garcia HG, Koszewski IJ, Nyquist GG, Rosen MR, Huntley C, Evans JJ, Rabinowitz MR. A cadaveric model for measuring sinonasal continuous positive airway pressure—a proof‐of‐concept study. International Forum Of Allergy & Rhinology 2018, 9: 197-203. PMID: 30431712, DOI: 10.1002/alr.22235.Peer-Reviewed Original ResearchConceptsSphenoid sinusPressure recordingsContinuous positive airway pressurePositive pressure therapyPositive airway pressureCommon respiratory disorderObstructive sleep apneaCadaver modelAnterior skull baseQuality of lifeFresh cadaver headsMiddle turbinate medializationSkull base surgeryIntraclass correlation coefficientPostoperative CPAPSellar bone