Cardiotoxicity and Cardioprotection in Childhood Cancer
Lipshultz SE, Sambatakos P, Maguire M, Karnik R, Ross SW, Franco VI, Miller TL. Cardiotoxicity and Cardioprotection in Childhood Cancer. Acta Haematologica 2014, 132: 391-399. PMID: 25228565, DOI: 10.1159/000360238.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAnthracycline cumulative doseAdverse late effectsSignificant cardiovascular diseaseUse of dexrazoxaneLong-term cardioprotectionAnthracycline chemotherapyCardiovascular damageCardioprotective strategiesOncological efficacyCardiac damageBlack raceCumulative doseFemale sexRisk factorsChildhood cancerCardiotoxic effectsCardiovascular diseaseLate effectsHigh riskHigh doseGenetic predispositionCardiotoxicityYounger ageTrisomy 21Nutritional supplements