2009
Medication and Parent Training in Children With Pervasive Developmental Disorders and Serious Behavior Problems: Results From a Randomized Clinical Trial
Aman MG, Mcdougle CJ, Scahill L, Handen B, Arnold LE, Johnson C, Stigler KA, Bearss K, Butter E, Swiezy NB, Sukhodolsky DD, Ramadan Y, Pozdol SL, Nikolov R, Lecavalier L, Kohn AE, Koenig K, Hollway JA, Korzekwa P, Gavaletz A, Mulick JA, Hall KL, Dziura J, Ritz L, Trollinger S, Yu S, Vitiello B, Wagner A, Network F. Medication and Parent Training in Children With Pervasive Developmental Disorders and Serious Behavior Problems: Results From a Randomized Clinical Trial. Journal Of The American Academy Of Child & Adolescent Psychiatry 2009, 48: 1143-1154. PMID: 19858761, PMCID: PMC3142923, DOI: 10.1097/chi.0b013e3181bfd669.Peer-Reviewed Original ResearchConceptsPervasive developmental disorderClinical trialsClinical Global Impressions-Improvement scoreAberrant Behavior Checklist IrritabilityParallel-group clinical trialParent trainingBehavioral problemsDevelopmental disordersRisperidone doseRisperidone monotherapyHyperactivity/noncompliance subscaleSevere behavioral problemsCOMB groupPT sessionsQuestionnaire scoresHSQ scoresMedicationsGreater reductionChildrenPrimary measureRisperidoneSignificant reductionStereotypic behaviorScoresDose
2006
Autismo: tratamentos psicofarmacológicos e áreas de interesse para desenvolvimentos futuros
Nikolov R, Jonker J, Scahill L. Autismo: tratamentos psicofarmacológicos e áreas de interesse para desenvolvimentos futuros. Brazilian Journal Of Psychiatry 2006, 28: s39-s46. PMID: 16791391, DOI: 10.1590/s1516-44462006000500006.Peer-Reviewed Original ResearchConceptsPervasive developmental disorderDevelopmental disordersChronic neurodevelopmental disorderCurrent pharmacotherapyMedication treatmentTreatment optionsNew medicationsSide effectsCore symptomsBehavior symptomsDisordersNeurodevelopmental disordersAutistic disorderEarly childhoodSymptomsTreatmentSubstantial needSignificant numberMaladaptive behaviorsMedicationsPharmacotherapyPatientsPathophysiologyDisease