1999
In vitro selection of deoxyribozymes with DNA capping activity.
Li Y, Liu Y, Breaker R. In vitro selection of deoxyribozymes with DNA capping activity. Nucleic Acids Symposium Series 1999, 42: 237-8. PMID: 10780467, DOI: 10.1093/nass/42.1.237.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateBase SequenceBinding SitesCatalysisConserved SequenceDNADNA, CatalyticDNA, Single-StrandedOligodeoxyribonucleotides
1996
In vitro selection of self-cleaving DNAs
Carmi N, Shultz L, Breaker R. In vitro selection of self-cleaving DNAs. Cell Chemical Biology 1996, 3: 1039-1046. PMID: 9000012, DOI: 10.1016/s1074-5521(96)90170-2.Peer-Reviewed Original ResearchConceptsIndividual catalystsCatalytic DNAEnzyme-like activityChemical transformationsSole cofactorRate enhancementAdditional reactionsCu2DNA enzymeCatalystDNA cleavageBiological contextVitro SelectionUncatalyzed rateOxidative mechanismsDNAFurther optimizationDistinct classesRibozymeHydroxylDeoxyribozymesBiocatalystReactionCleavageCofactor
1993
Synthesis and properties of adenosine oligonucleotide analogues containing methylene groups in place of phosphodiester 5'-oxygens.
Breaker R, Gough G, Gilham P. Synthesis and properties of adenosine oligonucleotide analogues containing methylene groups in place of phosphodiester 5'-oxygens. Biochemistry 1993, 32: 9125-8. PMID: 8396423, DOI: 10.1021/bi00086a017.Peer-Reviewed Original Research