2005
Gene expression control: Harnessing RNA switches
Breaker R. Gene expression control: Harnessing RNA switches. Gene Therapy 2005, 12: 725-726. PMID: 19202632, DOI: 10.1038/sj.gt.3302461.Peer-Reviewed Original Research
2002
Deoxyribozymes: new activities and new applications
Emilsson G, Breaker R. Deoxyribozymes: new activities and new applications. Cellular And Molecular Life Sciences 2002, 59: 596-607. PMID: 12022469, PMCID: PMC11337523, DOI: 10.1007/s00018-002-8452-4.Peer-Reviewed Original Research
2000
Allosteric nucleic acid catalysts
Soukup G, Breaker R. Allosteric nucleic acid catalysts. Current Opinion In Structural Biology 2000, 10: 318-325. PMID: 10851196, DOI: 10.1016/s0959-440x(00)00090-7.Peer-Reviewed Original Research
1999
Catalytic DNA: in training and seeking employment
Breaker R. Catalytic DNA: in training and seeking employment. Nature Biotechnology 1999, 17: 422-423. PMID: 10331790, DOI: 10.1038/8588.Peer-Reviewed Original Research
1995
Self-Incorporation of coenzymes by ribozymes
Breaker R, Joyce G. Self-Incorporation of coenzymes by ribozymes. Journal Of Molecular Evolution 1995, 40: 551-558. PMID: 7643406, DOI: 10.1007/bf00160500.Peer-Reviewed Original ResearchConceptsFunctional groupsCoenzyme analoguesAdditional functional groupsChemical functional groupsChemical moietiesTransfer reactionsCovalent attachmentRNA enzymeAbsence of proteinStandard nucleotidesCatalysisCatalytic functionRibozyme activityRNA worldRibozymeMoietyAnaloguesCoenzymeCoA-SHMoleculesReaction
1994
Inventing and improving ribozyme function: Rational design versus iterative selection methods
Breaker R, Joyce G. Inventing and improving ribozyme function: Rational design versus iterative selection methods. Trends In Biotechnology 1994, 12: 268-275. PMID: 7519862, DOI: 10.1016/0167-7799(94)90138-4.Peer-Reviewed Original Research