2001
Cooperative binding of effectors by an allosteric ribozyme
Jose A, Soukup G, Breaker R. Cooperative binding of effectors by an allosteric ribozyme. Nucleic Acids Research 2001, 29: 1631-1637. PMID: 11266567, PMCID: PMC31269, DOI: 10.1093/nar/29.7.1631.Peer-Reviewed Original ResearchConceptsAllosteric ribozymesCooperative bindingModular rational designAbsence of effectorsAllosteric proteinsRNA modulesRNA structureMolecular switchAllosteric effectorsFirst bindsFunctional complexityEffectorsDifferent effectorsInduces formationFMNStructural studiesRNARibozymeRibozyme constructsBindingRational designProteinBindsSitesConcert
1999
Allosteric ribozymes sensitive to the second messengers cAMP and cGMP.
Koizumi M, Kerr J, Soukup G, Breaker R. Allosteric ribozymes sensitive to the second messengers cAMP and cGMP. Nucleic Acids Symposium Series 1999, 42: 275-6. PMID: 10780486, DOI: 10.1093/nass/42.1.275.Peer-Reviewed Original Research
1994
Inventing and improving ribozyme function: Rational design versus iterative selection methods
Breaker R, Joyce G. Inventing and improving ribozyme function: Rational design versus iterative selection methods. Trends In Biotechnology 1994, 12: 268-275. PMID: 7519862, DOI: 10.1016/0167-7799(94)90138-4.Peer-Reviewed Original Research