2023
Exploiting natural riboswitches for aptamer engineering and validation
Mohsen M, Midy M, Balaji A, Breaker R. Exploiting natural riboswitches for aptamer engineering and validation. Nucleic Acids Research 2023, 51: 966-981. PMID: 36617976, PMCID: PMC9881172, DOI: 10.1093/nar/gkac1218.Peer-Reviewed Original ResearchConceptsNatural riboswitchesRiboswitch aptamerReporter gene expressionSecondary structure featuresRNA poolExpression platformVivo functionGene expressionSurvival mechanismRNA sequencesStructural featuresRiboswitchAptamer selectionSmall moleculesSequenceAptamerCellsGuanineTest tubeFuture effortsSelectionSelection strategyExpressionPoolAptamer engineering
2006
Riboswitches: Natural Metabolite‐binding RNAs Controlling Gene Expression
Roth A, Welz R, Breaker R. Riboswitches: Natural Metabolite‐binding RNAs Controlling Gene Expression. 2006, 191-207. DOI: 10.1002/3527608192.ch8.Peer-Reviewed Original Research