2024
Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis
Ram C, Yousef S, Ma W, Vallabhajosyula I, Singh S, Agarwal R, Milewski R, Assi R, Patel P, Williams M, Geirsson A, Vallabhajosyula P. Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis. Scientific Reports 2024, 14: 4952. PMID: 38418864, PMCID: PMC10902341, DOI: 10.1038/s41598-024-52660-w.Peer-Reviewed Original ResearchConceptsAortic valve replacementSevere aortic stenosisAfrican American raceArea Deprivation IndexAortic stenosisSevere ASArea deprivation index rankAortic valve replacement ratesAmerican raceAortic valve interventionPresentation of sepsisDiagnosis of ASADI groupValve replacementValve interventionDeprived neighbourhoodsAV interventionDisadvantaged neighborhoodsPatientsFemale genderDeprivation indexHigh-ADI groupLow-ADI groupStenosisRace
2022
Screening Tool to Identify Patients with Advanced Aortic Valve Stenosis
Yousef S, Amabile A, Ram C, Huang H, Korutla V, Singh S, Agarwal R, Assi R, Milewski RK, Zhang Y, Patel PA, Krane M, Geirsson A, Vallabhajosyula P. Screening Tool to Identify Patients with Advanced Aortic Valve Stenosis. Journal Of Clinical Medicine 2022, 11: 4386. PMID: 35956007, PMCID: PMC9369431, DOI: 10.3390/jcm11154386.Peer-Reviewed Original ResearchAortic stenosisRisk prediction modelTertiary academic care centerAcademic care centerSevere aortic stenosisAortic valve stenosisBody mass indexCross-sectional analysisLogistic regression modelsLarge population cohortCardiovascular comorbiditiesEchocardiographic studyValve stenosisMass indexClinical burdenClinical variablesUnique patientsC-statisticCare centerMale genderPatient riskComorbidity variablesC-indexMultivariable modelInclusion criteriaOne and Five-Year Mortality Risk Prediction in Patients with Moderate and Severe Aortic Stenosis
Yousef S, Amabile A, Huang H, Agarwal R, Singh S, Ram C, Milewski RK, Assi R, Zhang Y, Krane M, Geirsson A, Vallabhajosyula P. One and Five-Year Mortality Risk Prediction in Patients with Moderate and Severe Aortic Stenosis. Journal Of Clinical Medicine 2022, 11: 2949. PMID: 35629075, PMCID: PMC9146915, DOI: 10.3390/jcm11102949.Peer-Reviewed Original ResearchSevere aortic stenosisAortic stenosisRisk prediction modelPatient characteristicsDegree of ASCox proportional hazards modelModerate aortic stenosisSevere AS patientsUnadjusted overall mortalityLow ejection fractionProportional hazards modelMortality risk predictionCardiac comorbiditiesEchocardiographic evidenceOnly patientsEjection fractionOverall mortalityAS patientsHigh morbidityComplex patientsC-statisticSingle institutionIndividualized riskRisk scoreHazards model