2024
Clinical Effectiveness of Genetic Testing Guidelines in Patients with Thoracic Aortic Aneurysms
Erez E, Acuna Higaki A, Cupo M, Phu T, Verma S, Assi R, Vallabhajosyula P. Clinical Effectiveness of Genetic Testing Guidelines in Patients with Thoracic Aortic Aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2024 PMID: 39321868, DOI: 10.1016/j.jtcvs.2024.09.026.Peer-Reviewed Original ResearchFeatures of connective tissue diseaseThoracic aortic diseaseConnective tissue diseaseThoracic aortic aneurysmGenetic testing guidelinesSyndromic featuresMutation rateFamily historyVUS rateAortic aneurysmPrimary genesGenetic testingAssociated with thoracic aortic diseaseThoracic aorta diameterTesting guidelinesAorta diameterPathogen mutation rateAortic diseaseRisk stratificationSecondary genesPathogenic mutationsTissue diseaseClinical effectsVUSGenes
2021
Patterns of Surveillance Imaging for Incidentally Detected Ascending Aortic Aneurysms
Weininger G, Mori M, Shang M, Degife E, Amick M, Yousef S, Assi R, Milewski R, Geirsson A, Vallabhajosyula P. Patterns of Surveillance Imaging for Incidentally Detected Ascending Aortic Aneurysms. The Annals Of Thoracic Surgery 2021, 113: 125-130. PMID: 33609548, DOI: 10.1016/j.athoracsur.2021.02.010.Peer-Reviewed Original ResearchConceptsAneurysm sizeLogistic regression modelsAortic aneurysmTomography scanCardiac surgeonsHigh-risk patient populationHigh-risk patientsAscending Aortic AneurysmLow clinical penetranceMedian aneurysm sizeYear of detectionPatterns of surveillanceMedian followCare patientsRegression modelsSurveillance imagingSurveillance intervalsPatient populationIncidental detectionFamily historyClinical penetrancePatientsPatient's aneurysmSilent killerTimely intervention