2022
Identifying quality of life outcome patterns to inform treatment choices in ischemic cardiomyopathy
Mori M, Mark DB, Khera R, Lin H, Jones P, Huang C, Lu Y, Geirsson A, Velazquez EJ, Spertus JA, Krumholz HM. Identifying quality of life outcome patterns to inform treatment choices in ischemic cardiomyopathy. American Heart Journal 2022, 254: 12-22. PMID: 35932911, DOI: 10.1016/j.ahj.2022.07.007.Peer-Reviewed Original ResearchMeSH KeywordsCardiomyopathiesClinical Trials as TopicCoronary Artery BypassHumansMyocardial IschemiaQuality of LifeTreatment OutcomeConceptsCoronary artery bypass surgeryGuideline-directed medical therapyTreatment choiceBetter outcomesIschemic cardiomyopathyQOL outcomesQoL dataKansas City Cardiomyopathy Questionnaire overall summary scoreQOL trajectoriesOutcome patternsIschemic Heart Failure (STICH) trialHeart Failure TrialMain baseline predictorsArtery bypass surgeryOverall summary scoreDifferent treatment choicesLogistic regression modelsBypass surgeryMedical therapySurgical treatmentFailure TrialLife scoresQOL scoresPatient's probabilityBaseline predictors
2017
Predictors of Death in Adults With Duchenne Muscular Dystrophy–Associated Cardiomyopathy
Cheeran D, Khan S, Khera R, Bhatt A, Garg S, Grodin JL, Morlend R, Araj FG, Amin AA, Thibodeau JT, Das S, Drazner MH, Mammen PPA. Predictors of Death in Adults With Duchenne Muscular Dystrophy–Associated Cardiomyopathy. Journal Of The American Heart Association 2017, 6: e006340. PMID: 29042427, PMCID: PMC5721845, DOI: 10.1161/jaha.117.006340.Peer-Reviewed Original ResearchConceptsDuchenne muscular dystrophyDMD patientsPrognostic factorsDMD populationCardiac biomarkersHigh-risk cardiovascular populationLower body mass indexAdult DMD patientsHeart failure medicationsPredictors of deathAlanine aminotransferase levelsElevated cardiac biomarkersPoor prognostic factorMaximum inspiratory pressureBody mass indexElectronic medical recordsCardiomyopathy clinicMedian followAminotransferase levelsBaseline characteristicsCardiovascular populationRetrospective cohortConsecutive patientsMass indexWorse prognosis