2000
Granulocyte-Macrophage Colony-Stimulating Factor Priming plus Papillomavirus E6 DNA Vaccination: Effects on Papilloma Formation and Regression in the Cottontail Rabbit Papillomavirus-Rabbit Model
Leachman S, Tigelaar R, Shlyankevich M, Slade M, Irwin M, Chang E, Wu T, Xiao W, Pazhani S, Zelterman D, Brandsma J. Granulocyte-Macrophage Colony-Stimulating Factor Priming plus Papillomavirus E6 DNA Vaccination: Effects on Papilloma Formation and Regression in the Cottontail Rabbit Papillomavirus-Rabbit Model. Journal Of Virology 2000, 74: 8700-8708. PMID: 10954571, PMCID: PMC116381, DOI: 10.1128/jvi.74.18.8700-8708.2000.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiopsyCottontail rabbit papillomavirusDisease Models, AnimalDisease-Free SurvivalDNA, ViralGene Transfer TechniquesGenetic VectorsGranulocyte-Macrophage Colony-Stimulating FactorImmunohistochemistryIn Situ HybridizationPapillomaPapillomavirus InfectionsRabbitsTumor Virus InfectionsVaccines, DNAViral VaccinesConceptsGM-CSF primingGM-CSF treatmentDNA vaccinationDNA inoculationPapilloma formationGM-CSFProfessional antigen-presenting cellsMajor histocompatibility complex classDisease-free survivalVaccination-challenge experimentsAntigen-presenting cellsII-positive cellsGranulocyte-macrophage colony-stimulating factorHistocompatibility complex classColony-stimulating factorGranulocyte-macrophage colonyPapilloma volumeVaccination regimenClinical outcomesCutaneous sitesDNA vaccineViral challengePapilloma growthControl rabbitsCombination treatment
1997
Intracutaneous vaccination of rabbits with the cottontail rabbit papillomavirus (CRPV) L1 gene protects against virus challenge
Sundaram P, Tigelaar R, Brandsma J. Intracutaneous vaccination of rabbits with the cottontail rabbit papillomavirus (CRPV) L1 gene protects against virus challenge. Vaccine 1997, 15: 664-671. PMID: 9178468, DOI: 10.1016/s0264-410x(96)00237-x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, ViralAntigens, ViralBiolisticsCell DivisionCHO CellsCloning, MolecularCottontail rabbit papillomavirusCricetinaeEpitopes, T-LymphocyteInjections, SubcutaneousNeutralization TestsPapillomavirus InfectionsRabbitsT-LymphocytesTumor Virus InfectionsVaccines, SyntheticViral Structural ProteinsViral VaccinesConceptsCottontail rabbit papillomavirusHigh titered antibodiesVaccination of rabbitsCellular proliferative responseMajor capsid protein L1Capsid protein L1Papillomavirus infectionTitered antibodiesDNA vaccineVirus challengeProliferative responseIntracutaneous vaccinationPapilloma formationRabbit papillomavirusVirus-like particlesL1 geneL1 DNARabbitsVaccinationAntibodies