2022
Oxygen administration during surgery and postoperative organ injury: observational cohort study
McIlroy D, Shotwell M, Lopez M, Vaughn M, Olsen J, Hennessy C, Wanderer J, Semler M, Rice T, Kheterpal S, Billings F, Group M, Cuff G, Freundlich R, Kurz A, Naik B, Mathis M, Schonberger R. Oxygen administration during surgery and postoperative organ injury: observational cohort study. The BMJ 2022, 379: e070941. PMID: 36450405, PMCID: PMC9710248, DOI: 10.1136/bmj-2022-070941.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAdultAgedCohort StudiesFemaleHeart InjuriesHumansLung InjuryMiddle AgedOxygenPostoperative PeriodConceptsAcute kidney injuryObservational cohort studyLung injuryKidney injuryMyocardial injuryOxygen administrationGreater oddsCohort studyMedian age 59 yearsHospital discharge diagnosis codesGlobal Outcomes criteriaAge 59 yearsHours of surgeryDischarge diagnosis codesPotential confounding variablesHemoglobin oxygen saturationPostoperative kidneyPrimary endpointAdult patientsMedian durationOrgan injurySerum troponinEndotracheal intubationGeneral anesthesiaKidney diseaseAssociation between choice of reversal agent for neuromuscular block and postoperative pulmonary complications in patients at increased risk undergoing non-emergency surgery: STIL-STRONGER, a multicentre matched cohort study
Colquhoun D, Vaughn M, Bash L, Janda A, Shah N, Ghaferi A, Sjoding M, Mentz G, Kheterpal S, Committee M, Craft R, Domino K, Freundlich R, Mathis M, McCormick P, Naik B, Ruiz J, Schonberger R, Schroeder R, Stewart A, Taicher B, Tingle S, Togioka B, Urman R, Vachhani S. Association between choice of reversal agent for neuromuscular block and postoperative pulmonary complications in patients at increased risk undergoing non-emergency surgery: STIL-STRONGER, a multicentre matched cohort study. British Journal Of Anaesthesia 2022, 130: e148-e159. PMID: 35691703, PMCID: PMC9875908, DOI: 10.1016/j.bja.2022.04.023.Peer-Reviewed Original ResearchConceptsPostoperative pulmonary complicationsPulmonary complicationsNon-emergency surgeryRespiratory failureCohort studyNeuromuscular blockReversal agentsAnesthesiologists physical status 3Primary composite outcomeCohort of patientsUse of sugammadexIntra-abdominal surgeryOccurrence of pneumoniaBody mass indexSource of morbidityNeuromuscular blocking agentsStatus 3Complication outcomesComposite outcomeMajor surgeryPrimary outcomeMass indexTracheal intubationGeneral anesthesiaMulticenter Perioperative Outcomes Group
2015
Ambulatory Medical Follow-Up in the Year After Surgery and Subsequent Survival in a National Cohort of Veterans Health Administration Surgical Patients
Schonberger RB, Dai F, Brandt C, Burg MM. Ambulatory Medical Follow-Up in the Year After Surgery and Subsequent Survival in a National Cohort of Veterans Health Administration Surgical Patients. Journal Of Cardiothoracic And Vascular Anesthesia 2015, 30: 671-679. PMID: 27021176, PMCID: PMC5499041, DOI: 10.1053/j.jvca.2015.12.019.Peer-Reviewed Original ResearchConceptsFirst postoperative yearPostoperative yearNational cohortPostsurgical yearSurgical patientsLong-term postoperative survivalVeterans Health Administration facilitiesFirst postsurgical yearRetrospective cohort studyPostoperative year 1Day of surgeryAmbulatory medical careHazard of deathPostoperative year 2Medical Follow-UpYear 2US veterans' hospitalsYear 1Cause mortalityPostoperative survivalCohort studyPatient subgroupsCare coordinationFollow-upUS veteransBalancing Model Performance and Simplicity to Predict Postoperative Primary Care Blood Pressure Elevation
Schonberger RB, Dai F, Brandt CA, Burg MM. Balancing Model Performance and Simplicity to Predict Postoperative Primary Care Blood Pressure Elevation. Anesthesia & Analgesia 2015, 121: 632-641. PMID: 26214552, PMCID: PMC4545382, DOI: 10.1213/ane.0000000000000860.Peer-Reviewed Original ResearchConceptsClinic blood pressureBlood pressureNet reclassification indexSurgical patientsReclassification indexLong-term cardiovascular morbidityBlood pressure thresholdBroader public health effortsPreoperative blood pressureBlood pressure elevationComplex logistic regression modelLong-term morbidityBlood pressure readingsPerioperative blood pressureOutpatient clinic followBlood pressure measurementsRole of anesthesiologistsPublic health effortsPossible beneficial effectsLongitudinal patient careLogistic regression modelsCardiovascular morbidityClinic followHypertension historyHypertensive range
2013
The Problem of Controlling for Imperfectly Measured Confounders on Dissimilar Populations: A Database Simulation Study
Schonberger RB, Gilbertsen T, Dai F. The Problem of Controlling for Imperfectly Measured Confounders on Dissimilar Populations: A Database Simulation Study. Journal Of Cardiothoracic And Vascular Anesthesia 2013, 28: 247-254. PMID: 23962461, PMCID: PMC3926910, DOI: 10.1053/j.jvca.2013.03.014.Peer-Reviewed Original ResearchAdrenergic beta-AntagonistsAlgorithmsAtenololBiasCardiac Surgical ProceduresCohort StudiesComorbidityComputer SimulationData Interpretation, StatisticalDatabases, FactualDrug TherapyHumansInternational Classification of DiseasesLogistic ModelsMetoprololModels, StatisticalMonte Carlo MethodObservational Studies as TopicPostoperative ComplicationsPrevalencePropensity ScoreRetrospective Studies
2012
Atenolol is Associated With Lower Day-of-Surgery Heart Rate Compared to Long- and Short-Acting Metoprolol
Schonberger RB, Brandt C, Feinleib J, Dai F, Burg MM. Atenolol is Associated With Lower Day-of-Surgery Heart Rate Compared to Long- and Short-Acting Metoprolol. Journal Of Cardiothoracic And Vascular Anesthesia 2012, 27: 298-304. PMID: 22889605, PMCID: PMC3557658, DOI: 10.1053/j.jvca.2012.06.021.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAgedAmbulatory Surgical ProceduresAntihypertensive AgentsAtenololChemistry, PharmaceuticalCohort StudiesConfidence IntervalsDelayed-Action PreparationsFemaleHeart RateHemodynamicsHumansLeast-Squares AnalysisLinear ModelsMaleMetoprololMiddle AgedOutpatientsPatient CompliancePropensity ScoreTreatment OutcomeConceptsBeats/minTwice-daily dosing regimensAmbulatory surgical patientsHeart rateSurgical patientsDosing regimensMetoprolol formulationsPrimary care visitsDay of surgeryRetrospective observational studyVeterans Administration HospitalGeneral linear modelHeart rate differencesΒ-blocker typeCare visitsAdministration HospitalObservational studyPatientsMetoprololAtenololMetoprolol succinateRegimensDaysLow dayMin