Renalase protects against cisplatin acute kidney injury in mice
Desir G, Wang L, Velazquez H, Moeckel G, Safirstein R. Renalase protects against cisplatin acute kidney injury in mice. The FASEB Journal 2013, 27: 910.7-910.7. DOI: 10.1096/fasebj.27.1_supplement.910.7.Peer-Reviewed Original ResearchCisplatin acute kidney injuryAcute kidney injuryRenalase expressionKidney injuryCisplatin-induced acute kidney injuryIschemic acute kidney injuryRenal injury scoreUseful therapeutic optionHK-2 cellsImportant clinical syndromeRenalase deficiencyTubular necrosisPro-survival signalsTherapeutic optionsClinical syndromeInjury scorePlasma creatinineKO miceEffective therapyRenalaseBCL2 expressionMarked reductionProtective actionCaspase-3Injury