Efficacy of agents for pharmacologic conversion of atrial fibrillation and subsequent maintenance of sinus rhythm: a meta-analysis of clinical trials.
Miller M, McNamara R, Segal J, Kim N, Robinson K, Goodman S, Powe N, Bass E. Efficacy of agents for pharmacologic conversion of atrial fibrillation and subsequent maintenance of sinus rhythm: a meta-analysis of clinical trials. The Journal Of Family Practice 2000, 49: 1033-46. PMID: 11093570.Peer-Reviewed Original ResearchConceptsAF conversionAtrial fibrillationSinus rhythmOdds ratioModerate evidenceMultiple antiarrhythmic agentsAdverse event ratesClinical trials databasesEfficacy of agentsAdverse event dataPharmacologic conversionAdverse eventsRandomized trialsTrials databasesCochrane CollaborationAntiarrhythmic agentsClinical trialsStudy qualityAgent efficacySuggestive evidenceEvent ratesFlecainideDisopyramideRelative efficacyStrong evidence