1995
Risperidone Treatment of Children and Adolescents with Chronic Tic Disorders: A Preliminary Report
LOMBROSO P, SCAHILL L, KING R, LYNCH K, CHAPPELL P, PETERSON B, McDOUGLE C, LECKMAN J. Risperidone Treatment of Children and Adolescents with Chronic Tic Disorders: A Preliminary Report. Journal Of The American Academy Of Child & Adolescent Psychiatry 1995, 34: 1147-1152. PMID: 7559308, DOI: 10.1097/00004583-199509000-00011.Peer-Reviewed Original ResearchConceptsChronic tic disorderTic disordersObsessive-compulsive disorderChronic motor tic disorderYale Global Tic Severity ScaleDopamine-blocking propertiesOpen-label trialFrequent side effectsEfficacy of risperidoneMotor tic disorderShort-term safetyTic Severity ScaleComorbid obsessive-compulsive disorderYale-Brown Obsessive Compulsive ScaleObsessive Compulsive ScaleClinical responseRisperidone treatmentMean ageTic scoreSeverity ScaleSide effectsTourette syndromeComorbid diagnosesTic frequencyWeight gain
1994
Fluvoxamine Open-Label Treatment of Adolescent Inpatients with Obsessive-Compulsive Disorder or Depression
APTER A, RATZONI G, KING R, WEIZMAN A, IANCU I, BINDER M, RIDDLE M. Fluvoxamine Open-Label Treatment of Adolescent Inpatients with Obsessive-Compulsive Disorder or Depression. Journal Of The American Academy Of Child & Adolescent Psychiatry 1994, 33: 342-348. PMID: 8169178, DOI: 10.1097/00004583-199403000-00007.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderMajor depressive disorderYale-Brown Obsessive Compulsive ScaleOvert Aggression ScaleBeck Depression InventorySide effectsSuicide Potential ScaleSpecific serotonin uptake inhibitorAdolescent inpatientsEfficacy of fluvoxamineOpen-label trialOpen-label treatmentCommon side effectsSerotonin uptake inhibitorSerious side effectsShort-term treatmentY-BOCS scoresObsessive Compulsive ScaleDaily dosesTarget symptomsDepressive disorderDemonstrated efficacyInvestigational basisUptake inhibitorFluvoxamine