Comparison of the prevalence and associated factors of chronic kidney disease diagnosed by serum creatinine or cystatin C among young people living with HIV in Uganda
Nasuuna E, Tomlinson L, Kalyesubula R, Dziva Chikwari C, Castelnuovo B, Manabe Y, Nakanjako D, Weiss H. Comparison of the prevalence and associated factors of chronic kidney disease diagnosed by serum creatinine or cystatin C among young people living with HIV in Uganda. BMC Nephrology 2024, 25: 422. PMID: 39587464, PMCID: PMC11590532, DOI: 10.1186/s12882-024-03865-8.Peer-Reviewed Original ResearchConceptsAlbumin-creatinine ratioChronic kidney diseaseFactors associated with chronic kidney diseaseSerum creatinineAdjusted odds ratiosCystatin CKidney diseaseEarly diagnosisAssociated with chronic kidney diseasePrevalence of chronic kidney diseaseCompare serum creatinineCreatinine-based onesFactors of chronic kidney diseaseAssociated with high mortalityCases of chronic kidney diseaseDefinition of chronic kidney diseaseChronic kidney disease prevalenceCystatin C-based equationsCystatin C levelsEstimate adjusted odds ratiosMeasuring urinary albuminConfidence intervalsDiagnosis of chronic kidney diseaseMultivariate logistic regressionReduce disease progressionPrevalence of chronic kidney disease among young people living with HIV in Sub Saharan Africa: A systematic review and meta-analysis
Nasuuna E, Nanyeenya N, Kibirige D, Izudi J, Chikwari C, Kalyesubula R, Castelnuovo B, Tomlinson L, Weiss H. Prevalence of chronic kidney disease among young people living with HIV in Sub Saharan Africa: A systematic review and meta-analysis. PLOS ONE 2024, 19: e0301954. PMID: 39495780, PMCID: PMC11534254, DOI: 10.1371/journal.pone.0301954.Peer-Reviewed Original ResearchConceptsPrevalence of chronic kidney diseaseChronic kidney disease prevalenceCKD prevalenceSub-Saharan AfricaDefinition of chronic kidney diseaseChronic kidney diseaseMeta-analysisPublication biasGlomerular filtration rateSystematic reviewJoanna Briggs Institute checklistEligibility criteriaI-squared valuePooled prevalence of chronic kidney diseaseEstimates of CKD prevalenceAlbumin-to-creatinine ratioDerSimonian-Laird random-effects modelCross-sectional studyRisk of biasAfrican Journals OnlineAfrican Index MedicusCochran's Q testRandom-effects modelStandard definitionYoung peopleDiagnostic performance of an albuminuria point-of-care test in screening for chronic kidney disease among young people living with HIV in Uganda: a cross-sectional study
Nasuuna E, Kalyesubula R, Tomlinson L, Castelnuovo B, Okello E, Chikwari C, Weiss H. Diagnostic performance of an albuminuria point-of-care test in screening for chronic kidney disease among young people living with HIV in Uganda: a cross-sectional study. BMJ Open 2024, 14: e083221. PMID: 39153770, PMCID: PMC11331864, DOI: 10.1136/bmjopen-2023-083221.Peer-Reviewed Original ResearchConceptsPositive POC testCross-sectional studyChronic kidney diseaseDiagnostic performancePoint-of-care testingKidney diseaseHIV clinicPOC testingPOC testsBody mass index <Albumin-creatinine ratioPositive predictive valueUrinary excretion rateDiagnosis of chronic kidney diseaseYoung peopleYears of ageTherapy to adultsYPLHIVUrine dipstickCreatinine ratioDiagnosis of albuminuriaLogistic regressionPrimary outcomeAlbuminuriaHIV