1992
RNA-directed actions of 5-fluorouridine in hemin stimulated K-562 erythroleukemia cells.
Heimer R, Sartorelli A. RNA-directed actions of 5-fluorouridine in hemin stimulated K-562 erythroleukemia cells. Cancer Biochemistry Biophysics 1992, 12: 221-39. PMID: 1423209.Peer-Reviewed Original Research
1990
Reductions in γ-GIobin mRNA Levels Restricted to the Cytoplasm of 5-Fluorouridine Treated K-562 Human Erythroleukemia Cells
Heimer R, Sartorelli A. Reductions in γ-GIobin mRNA Levels Restricted to the Cytoplasm of 5-Fluorouridine Treated K-562 Human Erythroleukemia Cells. Oncology Research Featuring Preclinical And Clinical Cancer Therapeutics 1990, 2: 45-53. PMID: 2369550, DOI: 10.3727/095535490820874759.Peer-Reviewed Original ResearchConceptsGamma-globin mRNAHuman erythroleukemia cellsErythroleukemia cellsRNA synthesisRibosomal RNA synthesisNuclease protection analysisMRNA levelsMRNA degradationSteady-state levelsCytoplasmic mRNAMRNA speciesCytoplasmic rRNACytoplasmic endonucleaseMRNA synthesisBeta-actin mRNANorthern blottingProtection analysisUntreated control cellsProtein levelsMRNAControl cellsUntreated cellsUridine analogs
1989
RNA polymerase II transcripts as targets for 5-fluorouridine cytotoxicity: antagonism of 5-fluorouridine actions by α-amanitin
Heimer R, Sartorelli A. RNA polymerase II transcripts as targets for 5-fluorouridine cytotoxicity: antagonism of 5-fluorouridine actions by α-amanitin. Cancer Chemotherapy And Pharmacology 1989, 24: 80-86. PMID: 2731315, DOI: 10.1007/bf00263125.Peer-Reviewed Original ResearchMeSH KeywordsAdenosineAmanitinsCell DivisionCell Membrane PermeabilityChromatography, AffinityElectrophoresis, Agar GelHumansLeukemia, Erythroblastic, AcuteLysophosphatidylcholinesNucleic Acid HybridizationRNA Polymerase IIRNA PrecursorsRNA, MessengerTranscription, GeneticTumor Cells, CulturedTumor Stem Cell AssayUridine