2000
The Angular Gyrus in Developmental Dyslexia: Task-Specific Differences in Functional Connectivity Within Posterior Cortex
Pugh K, Mencl W, Shaywitz B, Shaywitz S, Fulbright R, Constable R, Skudlarski P, Marchione K, Jenner A, Fletcher J, Liberman A, Shankweiler D, Katz L, Lacadie C, Gore J. The Angular Gyrus in Developmental Dyslexia: Task-Specific Differences in Functional Connectivity Within Posterior Cortex. Psychological Science 2000, 11: 51-56. PMID: 11228843, DOI: 10.1111/1467-9280.00214.Peer-Reviewed Original ResearchConceptsDevelopmental dyslexiaAngular gyrusFunctional connectivityPhonological assemblyLeft hemispherePhonological processing domainTask-specific differencesLanguage-dominant left hemispherePosterior brain regionsTemporal lobe sitesDyslexic readersNeurobiological anomaliesPhonological performanceExplicit demandDyslexiaBrain regionsGyrusPosterior cortexTaskCompensatory roleVaried demandsPosterior regionDyslexicsConnectivityHemisphere
1998
Functional disruption in the organization of the brain for reading in dyslexia
Shaywitz S, Shaywitz B, Pugh K, Fulbright R, Constable R, Mencl W, Shankweiler D, Liberman A, Skudlarski P, Fletcher J, Katz L, Marchione K, Lacadie C, Gatenby C, Gore J. Functional disruption in the organization of the brain for reading in dyslexia. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 2636-2641. PMID: 9482939, PMCID: PMC19444, DOI: 10.1073/pnas.95.5.2636.Peer-Reviewed Original ResearchConceptsBrain activation patternsActivation patternsDyslexic readersFunctional disruptionFunctional magnetic resonanceAlphabetic charactersRelative underactivationPhonologic awarenessNeural signaturesPhonologic analysisSpoken wordsAnterior regionImpairmentNeural systemsPosterior regionDyslexiaMagnetic resonanceWordsOveractivationBrain