Association Between Antibiotic Redosing Before Incision and Risk of Incisional Site Infection in Children With Appendicitis
Cramm S, Chandler N, Graham D, Kunisaki S, Russell R, Blakely M, Lipskar A, Allukian M, Aronowitz D, Campbell B, Collins D, Commander S, Cowles R, DeFazio J, Esparaz J, Feng C, Griggs C, Guyer R, Hanna D, Kahan A, Keane O, Lamoshi A, Lopez C, Pace E, Regan M, Santore M, Scholz S, Tracy E, Williams S, Zhang L, Rangel S. Association Between Antibiotic Redosing Before Incision and Risk of Incisional Site Infection in Children With Appendicitis. Annals Of Surgery 2022, 278: e863-e869. PMID: 36317528, DOI: 10.1097/sla.0000000000005747.Peer-Reviewed Original ResearchConceptsIncisional surgical site infectionHour of incisionPediatric National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramSurgical Quality Improvement ProgramSite infectionQuality Improvement ProgramAntibiotic redosingIncisional surgical site infection rateMulticenter retrospective cohort studyDisease severityDiagnosis of appendicitisSurgical site infectionRetrospective cohort studyRedosing of antibioticsOperative report dataMultivariate logistic regressionHospital-level clusteringIncreased disease severityAntibiotic regimensInitial doseAntibiotic administrationPatient demographicsAntibiotic utilizationChart reviewAssociation of Gangrenous, Suppurative, and Exudative Findings With Outcomes and Resource Utilization in Children With Nonperforated Appendicitis
Cramm SL, Lipskar AM, Graham DA, Kunisaki SM, Griggs CL, Allukian M, Russell RT, Chandler NM, Santore MT, Aronowitz DI, Blakely ML, Campbell B, Collins DT, Commander SJ, Cowles RA, DeFazio JR, Echols JC, Esparaz JR, Feng C, Guyer RA, Hanna DN, He K, Kahan AM, Keane OA, Lamoshi A, Lopez CM, McLean SE, Pace E, Regan MD, Scholz S, Tracy ET, Williams SA, Zhang L, Rangel SJ, Chang A, Fitzgerald M, Middlesworth W, Finck C, Hackam D, Engwall-Gill A, Gerall C, Orlas C, Hwang R, Dantes G. Association of Gangrenous, Suppurative, and Exudative Findings With Outcomes and Resource Utilization in Children With Nonperforated Appendicitis. JAMA Surgery 2022, 157: 685-692. PMID: 35648410, PMCID: PMC9161124, DOI: 10.1001/jamasurg.2022.1928.Peer-Reviewed Original ResearchConceptsSurgical site infectionSite infectionExudative findingsPostoperative lengthOperative reportsNonperforated appendicitisNational Surgical Quality Improvement ProgramMultivariable mixed-effects regressionPostoperative surgical site infectionSurgical Quality Improvement ProgramPediatric National Surgical Quality Improvement ProgramMean postoperative lengthOrgan space infectionMulticenter cohort studyMedical record reviewCohort of childrenQuality Improvement ProgramPostoperative antibioticsCohort studyInpatient managementPatient characteristicsSecondary outcomesSpace infectionPrimary outcomeHospital revisits