2021
Trends in fundoplication volume for pediatric gastroesophageal reflux disease
Maassel NL, Shaughnessy MP, Solomon DG, Cowles RA. Trends in fundoplication volume for pediatric gastroesophageal reflux disease. Journal Of Pediatric Surgery 2021, 56: 1495-1499. PMID: 33745746, DOI: 10.1016/j.jpedsurg.2021.02.045.Peer-Reviewed Original ResearchConceptsGastro-esophageal reflux diseasePediatric Health Information SystemPediatric surgery fellowsReflux diseaseSurgical volumeCase volumeSevere gastro-esophageal reflux diseasePediatric gastroesophageal reflux diseaseICD-9/ICDTotal operative volumeGastroesophageal reflux diseaseGraduate Medical Education caseFellow case logsPatient characteristicsPatient demographicsPediatric surgeonsOperative volumePediatric surgical trainingSecondary analysisHealth information systemsAbstractTextCase logsFundoplicationNational dataRecent dataLaparoscopy is increasingly used for pediatric inguinal hernia repair
Shaughnessy MP, Maassel NL, Yung N, Solomon DG, Cowles RA. Laparoscopy is increasingly used for pediatric inguinal hernia repair. Journal Of Pediatric Surgery 2021, 56: 2016-2021. PMID: 33549307, DOI: 10.1016/j.jpedsurg.2021.01.032.Peer-Reviewed Original ResearchConceptsLaparoscopic inguinal hernia repairInguinal hernia repairHernia repairLaparoscopic repairCHA HospitalProcedure typePediatric Health Information SystemPediatric inguinal hernia repairStudy periodDefinitive prospective studiesLong-term outcomesTotal hospital costsUse of laparoscopyTen-year study periodIHR groupLaparoscopic groupYounger patientsProspective studyHospital costsOperative approachSurgeon preferencePediatric surgeonsHealth information systemsAbstractTextLaparoscopy
2012
Neuronal Serotonin Regulates Growth of the Intestinal Mucosa in Mice
Gross ER, Gershon MD, Margolis KG, Gertsberg ZV, Li Z, Cowles RA. Neuronal Serotonin Regulates Growth of the Intestinal Mucosa in Mice. Gastroenterology 2012, 143: 408-417.e2. PMID: 22609381, PMCID: PMC3687781, DOI: 10.1053/j.gastro.2012.05.007.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCholine O-AcetyltransferaseCholinergic NeuronsEnterochromaffin CellsIntestinal MucosaKetanserinMaleMiceMice, Inbred C57BLMice, KnockoutMuscarinic AntagonistsReceptor, Serotonin, 5-HT2AScopolamineSelective Serotonin Reuptake InhibitorsSerotonergic NeuronsSerotoninSerotonin AntagonistsSerotonin Plasma Membrane Transport ProteinsTryptophan HydroxylaseConceptsSelective serotonin re-uptake inhibitorsSerotonin re-uptake inhibitorsRe-uptake inhibitorsWild-type miceIntestinal mucosaSerotonin re-uptake transporterCholinergic submucosal neuronsIntestinal mucosal epitheliumRe-uptake transporterTryptophan hydroxylase 1Tryptophan hydroxylase 2Submucosal neuronsCholinergic neuronsCholine acetyltransferaseNeuronal serotoninMucosal growthMucosal epitheliumMucosal cellsSERT knockoutEpithelial proliferationAbstractTextMiceHydroxylase 2MucosaNeural precursors