1987
Role of the Na+/H+ antiporter in rat proximal tubule bicarbonate absorption.
Preisig PA, Ives HE, Cragoe EJ, Alpern RJ, Rector FC. Role of the Na+/H+ antiporter in rat proximal tubule bicarbonate absorption. Journal Of Clinical Investigation 1987, 80: 970-978. PMID: 2888788, PMCID: PMC442334, DOI: 10.1172/jci113190.Peer-Reviewed Original ResearchKinetic transport model for cellular regulation of pH and solute concentration in the renal proximal tubule
Verkman AS, Alpern RJ. Kinetic transport model for cellular regulation of pH and solute concentration in the renal proximal tubule. Biophysical Journal 1987, 51: 533-546. PMID: 3580482, PMCID: PMC1329926, DOI: 10.1016/s0006-3495(87)83379-9.Peer-Reviewed Original Research
1985
Amiloride inhibition of proximal tubular acidification
Howlin KJ, Alpern RJ, Rector FC. Amiloride inhibition of proximal tubular acidification. American Journal Of Physiology 1985, 248: f773-f778. PMID: 2988347, DOI: 10.1152/ajprenal.1985.248.6.f773.Peer-Reviewed Original ResearchConceptsProximal tubular acidificationLuminal amilorideBicarbonate absorptionX minTubular acidificationM amilorideSodium chloride absorptionLate proximal tubular fluidProximal tubular fluidPerfusion rateProximal acidificationVivo microperfusionTubular fluidKidney cortexChloride absorptionInhibition of acidificationPmol xAmilorideNonspecific inhibitionAmiloride inhibitionGreater inhibitionBrush border membrane vesiclesInhibitionGlucose effluxPotent inhibitor