1988
Regulation of cell pH by ambient bicarbonate, carbon dioxide tension, and pH in the rabbit proximal convoluted tubule.
Krapf R, Berry CA, Alpern RJ, Rector FC. Regulation of cell pH by ambient bicarbonate, carbon dioxide tension, and pH in the rabbit proximal convoluted tubule. Journal Of Clinical Investigation 1988, 81: 381-389. PMID: 3123519, PMCID: PMC329580, DOI: 10.1172/jci113330.Peer-Reviewed Original Research4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic AcidAmilorideAnimalsBicarbonatesCarbon DioxideFluoresceinsHydrogen-Ion ConcentrationIn Vitro TechniquesKidney Tubules, ProximalRabbits
1987
Basolateral membrane Na/base cotransport is dependent on CO2/HCO3 in the proximal convoluted tubule.
Krapf R, Alpern RJ, Rector FC, Berry CA. Basolateral membrane Na/base cotransport is dependent on CO2/HCO3 in the proximal convoluted tubule. The Journal Of General Physiology 1987, 90: 833-853. PMID: 2831294, PMCID: PMC2228880, DOI: 10.1085/jgp.90.6.833.Peer-Reviewed Original ResearchMeSH Keywords4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic AcidAcetazolamideAlkaliesAmilorideAnimalsBicarbonatesBiological TransportBuffersCarbon DioxideCarrier ProteinsCyanidesHydrogen-Ion ConcentrationIn Vitro TechniquesKidney Tubules, ProximalRabbitsSodiumSodium-Hydrogen ExchangersBasolateral membrane Cl/HCO3 exchange in the rat proximal convoluted tubule. Na-dependent and -independent modes.
Alpern RJ, Chambers M. Basolateral membrane Cl/HCO3 exchange in the rat proximal convoluted tubule. Na-dependent and -independent modes. The Journal Of General Physiology 1987, 89: 581-598. PMID: 2953859, PMCID: PMC2215917, DOI: 10.1085/jgp.89.4.581.Peer-Reviewed Original ResearchMeSH Keywords4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic AcidAdenosine TriphosphatasesAnimalsAnion Transport ProteinsBicarbonatesBiological TransportCell CompartmentationCell MembraneChloridesElectrophysiologyHydrogen-Ion ConcentrationKidney Tubules, ProximalMaleRatsSodiumConceptsCl/HCO3 exchangeNa-free solutionHCO3- exchangePeritubular NaCell pHHCO3- transport mechanismsBasolateral membraneProximal tubulesCoupling of NaMammalian proximal tubuleMeq/Similar increaseAmbient ClExtracellular fluidTubulesNa dependenceCotransporterNa concentrationCl concentrationsCellsSimilar amountsApical membrane chloride/base exchange in the rat proximal convoluted tubule.
Alpern RJ. Apical membrane chloride/base exchange in the rat proximal convoluted tubule. Journal Of Clinical Investigation 1987, 79: 1026-1030. PMID: 3558814, PMCID: PMC424279, DOI: 10.1172/jci112914.Peer-Reviewed Original Research4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic AcidAcid-Base EquilibriumAnimalsBasement MembraneBicarbonatesChloridesHydrogen-Ion ConcentrationKidney Tubules, ProximalMalePerfusionRatsRats, Inbred Strains
1986
Electrogenic sodium/bicarbonate cotransport in rabbit renal cortical basolateral membrane vesicles.
Akiba T, Alpern RJ, Eveloff J, Calamina J, Warnock DG. Electrogenic sodium/bicarbonate cotransport in rabbit renal cortical basolateral membrane vesicles. Journal Of Clinical Investigation 1986, 78: 1472-1478. PMID: 3782468, PMCID: PMC423898, DOI: 10.1172/jci112738.Peer-Reviewed Original ResearchMeSH Keywords4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic AcidAnimalsBicarbonatesBiological TransportFemaleHydrogen-Ion ConcentrationIn Vitro TechniquesKidney CortexKineticsRabbitsSodiumValinomycinConceptsMembrane vesiclesBasolateral membrane vesiclesSodium uptakePotassium diffusion potentialBicarbonate cotransporterSaturable stimulationSodium/bicarbonate cotransporterVesiclesRabbit renal cortexProteinDisulfonic stilbeneBicarbonate transportPresence of bicarbonateUptakeKinetic analysisRenal cortex