Ultrahigh-speed point scanning two-photon microscopy using high dynamic range silicon photomultipliers
Ching-Roa VD, Olson EM, Ibrahim SF, Torres R, Giacomelli MG. Ultrahigh-speed point scanning two-photon microscopy using high dynamic range silicon photomultipliers. Scientific Reports 2021, 11: 5248. PMID: 33664354, PMCID: PMC7933192, DOI: 10.1038/s41598-021-84522-0.Peer-Reviewed Original ResearchConceptsMaximum imaging rateSilicon photomultipliersAdvanced detection technologyPhoton detection rateDetection electronicsDetection technologyTwo-photon microscopyHigh sensitivityPhotomultiplier tubeDynamic rangeMicroscopyTwo-photon microscopeNoise ratioImaging rateOrders of magnitudeTwo-photonIntegration timeDetector designElectronicsPhotomultipliersMicroscopeConfocal microscopyTubeTechnologyDetection rate