2021
Ultrahigh-speed point scanning two-photon microscopy using high dynamic range silicon photomultipliers
Ching-Roa VD, Olson EM, Ibrahim SF, Torres R, Giacomelli MG. Ultrahigh-speed point scanning two-photon microscopy using high dynamic range silicon photomultipliers. Scientific Reports 2021, 11: 5248. PMID: 33664354, PMCID: PMC7933192, DOI: 10.1038/s41598-021-84522-0.Peer-Reviewed Original ResearchConceptsMaximum imaging rateSilicon photomultipliersAdvanced detection technologyPhoton detection rateDetection electronicsDetection technologyTwo-photon microscopyHigh sensitivityPhotomultiplier tubeDynamic rangeMicroscopyTwo-photon microscopeNoise ratioImaging rateOrders of magnitudeTwo-photonIntegration timeDetector designElectronicsPhotomultipliersMicroscopeConfocal microscopyTubeTechnologyDetection rate
2016
Evaluation of relational and NoSQL database architectures to manage genomic annotations
Schulz WL, Nelson BG, Felker DK, Durant TJ, Torres R. Evaluation of relational and NoSQL database architectures to manage genomic annotations. Journal Of Biomedical Informatics 2016, 64: 288-295. PMID: 27810480, DOI: 10.1016/j.jbi.2016.10.015.Peer-Reviewed Original ResearchConceptsRelational databaseNoSQL databasesQuery efficiencyData managementData storageDocument-oriented NoSQL databaseBiomedical data setsCommon relational databaseQuery retrievalDatabase technologyInformatics infrastructureRelational modelGenomic annotationsIndexingData setsArchitectureRetrievalAnnotationNew technologiesDatabaseTechnologySignificant advantagesRelative advantagesInfrastructureStorage