Primate model of chronic retinal neovascularization and vascular leakage
Patel C, Goody R, Hu W, Kurian A, James D, Torres R, Christie LA, Hohman T, Lawrence M. Primate model of chronic retinal neovascularization and vascular leakage. Experimental Eye Research 2020, 195: 108031. PMID: 32275921, PMCID: PMC7335215, DOI: 10.1016/j.exer.2020.108031.Peer-Reviewed Original ResearchConceptsGlial fibrillary acidic proteinVascular leakageVon Willebrand factorOptical coherence tomographyFluorescein angiographyRetinal neovascularizationPrimate modelCD105/endoglinNeovascular diseasesRetinal degenerationDL-alpha-aminoadipic acidBilateral intravitreal injectionsInner retinal edemaRetinal vascular leakageRetinal vascular pathologyVascular disease mechanismsColor fundus photographyMüller cell lossFibrillary acidic proteinExpression of vWFAfrican green monkeysCD68 immunoreactivityMacular telangiectasiaRetinal edemaIntravitreal injection