2018
Sera From Children After Cardiopulmonary Bypass Reduces Permeability of Capillary Endothelial Cell Barriers
Pierce RW, Zahr RA, Kandil S, Faustino EVS, Pober JS. Sera From Children After Cardiopulmonary Bypass Reduces Permeability of Capillary Endothelial Cell Barriers. Pediatric Critical Care Medicine 2018, 19: 609-618. PMID: 29652749, PMCID: PMC6037548, DOI: 10.1097/pcc.0000000000001553.Peer-Reviewed Original ResearchConceptsTransendothelial electrical resistanceCardiopulmonary bypassCapillary endothelial cellsEndothelial cellsCapillary leakPatient seraClaudin-5Pulmonary capillary endothelial cellsBarrier functionPulmonary microvascular endothelial cellsReal-time quantitative reverse transcription polymerase chain reactionTertiary pediatric hospitalQuantitative reverse transcription polymerase chain reactionCardiopulmonary bypass circuitCongenital heart diseaseReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionMicrovascular endothelial cellsEndothelial cell barrierCohort studyInflammatory mediatorsPediatric hospitalUnclear etiologyBarrier disruptionHeart diseaseComplete Recovery After Acute Zonisamide Overdose in an Adolescent Female
McStay C, Pierce R, Riley C. Complete Recovery After Acute Zonisamide Overdose in an Adolescent Female. Pediatric Emergency Care 2018, 34: e30-e31. PMID: 27749631, DOI: 10.1097/pec.0000000000000854.Peer-Reviewed Original ResearchConceptsElectrocardiographic abnormalitiesPartial seizuresEndotracheal intubationMechanical ventilationIntentional ingestionCase reportCatecholamine infusionMood disordersSingle agentComplete recoveryZonisamideAdolescent femalesIngestionSulfonamide drugsReportIntubationComplicationsPatientsOverdoseSeizuresInfusionAbnormalitiesWomen
2016
Association of thrombophilia and catheter‐associated thrombosis in children: a systematic review and meta‐analysis
Neshat‐Vahid S, Pierce R, Hersey D, Raffini LJ, Faustino EV. Association of thrombophilia and catheter‐associated thrombosis in children: a systematic review and meta‐analysis. Journal Of Thrombosis And Haemostasis 2016, 14: 1749-1758. PMID: 27306795, PMCID: PMC5035642, DOI: 10.1111/jth.13388.Peer-Reviewed Original ResearchConceptsDeep vein thrombosisCatheter-associated thrombosisCentral venous catheter useElevated factor VIII levelsAssociation of thrombophiliaRoutine thrombophilia testingVenous catheter useCochrane Central RegisterPediatric risk factorsPooled prevalence rateFactor VIII levelsProtein C deficiencyRandom-effects modelWeb of ScienceThrombophilic traitsCatheter useCentral RegisterCohort studyFV Leiden mutationVein thrombosisControlled TrialsVenous thrombosisPediatric studiesRisk factorsOdds ratio